Entity Details

Primary name TLR5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60602
EntryNameTLR5_HUMAN
FullNameToll-like receptor 5
TaxID9606
Evidenceevidence at protein level
Length858
SequenceStatuscomplete
DateCreated2002-01-31
DateModified2021-06-02

Ontological Relatives

GenesTLR5

GO terms

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GOName
GO:0002224 toll-like receptor signaling pathway
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0004888 transmembrane signaling receptor activity
GO:0005149 interleukin-1 receptor binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0032757 positive regulation of interleukin-8 production
GO:0034123 positive regulation of toll-like receptor signaling pathway
GO:0034146 toll-like receptor 5 signaling pathway
GO:0038023 signaling receptor activity
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
GO:0071260 cellular response to mechanical stimulus

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000157 Toll/interleukin-1 receptor homology (TIR) domainDomainDomain
IPR000483 Cysteine-rich flanking region, C-terminalDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR017241 Toll-like receptorFamilyFamily
IPR027176 Toll-like receptor 5FamilyFamily
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamilyFamilyHomologous superfamily

Diseases

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