Entity Details

Primary name REV3L_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60673
EntryNameREV3L_HUMAN
FullNameDNA polymerase zeta catalytic subunit
TaxID9606
Evidenceevidence at protein level
Length3130
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesREV3L

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0000724 double-strand break repair via homologous recombination
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006261 DNA-dependent DNA replication
GO:0016035 zeta DNA polymerase complex
GO:0042276 error-prone translesion synthesis
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0090305 nucleic acid phosphodiester bond hydrolysis

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR006133 DNA-directed DNA polymerase, family B, exonuclease domainDomainDomain
IPR006134 DNA-directed DNA polymerase, family B, multifunctional domainDomainDomain
IPR006172 DNA-directed DNA polymerase, family BFamilyFamily
IPR012337 Ribonuclease H-like superfamilyFamilyHomologous superfamily
IPR017964 DNA-directed DNA polymerase, family B, conserved siteSiteConserved site
IPR023211 DNA polymerase, palm domain superfamilyFamilyHomologous superfamily
IPR025687 C4-type zinc-finger of DNA polymerase deltaDomainDomain
IPR030559 DNA polymerase zeta catalytic subunitFamilyFamily
IPR032757 Domain of unknown function DUF4683DomainDomain
IPR036397 Ribonuclease H superfamilyFamilyHomologous superfamily
IPR042087 DNA polymerase family B, thumb domainFamilyHomologous superfamily
IPR043502 DNA/RNA polymerase superfamilyFamilyHomologous superfamily

Diseases

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