Entity Details

Primary name EIF3G_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75821
EntryNameEIF3G_HUMAN
FullNameEukaryotic translation initiation factor 3 subunit G
TaxID9606
Evidenceevidence at protein level
Length320
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesEIF3G

GO terms

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GOName
GO:0001732 formation of cytoplasmic translation initiation complex
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0006413 translational initiation
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
GO:0048471 perinuclear region of cytoplasm
GO:0075525 viral translational termination-reinitiation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR017334 Eukaryotic translation initiation factor 3 subunit GFamilyFamily
IPR024675 Eukaryotic translation initiation factor 3 subunit G, N-terminalDomainDomain
IPR034240 eIF3G, RNA recognition motifDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

39 interactions

InteractorPartnerSourcesPublicationsLink
EIF3G_HUMANEIF3B_HUMANBioGRID, DIP, HPRD, IntAct, MINT, UniProt14688252 18599441 18628297 22863883 22939629 24396066 24981860 26186194 26344197 28514442 30021884 9822659 details
EIF3G_HUMANMPH6_HUMANHPRD, IntAct15231747 details
EIF3G_HUMANAIFM1_HUMANBioGRID, HPRD, MINT17094969 details
EIF3G_HUMANEIF3I_HUMANBioGRID, DIP, IntAct, MINT17094969 18599441 22863883 22939629 24981860 26186194 26344197 28514442 details
EIF3G_HUMANEIF3H_HUMANBioGRID, HPRD, IntAct19615732 22939629 24981860 26186194 26344197 28514442 32269044 9822659 details
EIF3G_HUMANAAKG1_HUMANBioGRID, MINT21516116 details
EIF3G_HUMANGA45G_HUMANBioGRID, MINT21900206 details
EIF3G_HUMANPIN1_HUMANBioGRID, MINT21900206 details
EIF3G_HUMANPKN2_HUMANBioGRID, MINT21900206 details
EIF3G_HUMANSMN_HUMANBioGRID, MINT21900206 details
EIF3G_HUMANSYUA_HUMANBioGRID, MINT21900206 details
EIF3G_HUMANKITH_HUMANBioGRID, MINT21900206 details
EIF3G_HUMANGOGA2_HUMANBioGRID, IntAct25416956 details
EIF3G_HUMANFAM9B_HUMANBioGRID, IntAct25416956 details
EIF3G_HUMANEIF3C_HUMANBioGRID, DIP, HPRD, IntAct, MINT16189514 18599441 22939629 24396066 24981860 26186194 26344197 28514442 9822659 details
EIF3G_HUMANEIF3A_HUMANBioGRID, DIP, HPRD, IntAct, MINT14519125 18599441 22939629 24396066 24981860 26186194 26344197 28514442 9341143 9822659 details
EIF3G_HUMANACD_HUMANbhf-ucl, BioGRID21044950 details
EIF3G_HUMANPOTE1_HUMANbhf-ucl, BioGRID21044950 details
EIF3G_HUMANMI4GD_HUMANBioGRID, IntAct, UniProt23804756 32296183 details
EIF3G_HUMANEIF3D_HUMANBioGRID, HPRD, IntAct22190034 22939629 24981860 26186194 28514442 9822659 details
EIF3G_HUMANPELO_HUMANUniProt20406461 details
EIF3G_HUMANHD_HUMANBioGRID, IntAct, UniProt25959826 32814053 details
EIF3G_HUMANPALS2_HUMANBioGRID, HPRD15231747 details
EIF3G_HUMANEIF3K_HUMANBioGRID, HPRD14519125 22939629 24981860 26344197 details
EIF3G_HUMANEPB41_HUMANBioGRID, HPRD10887144 details
EIF3G_HUMANEIF3G_HUMANBioGRID, HPRD9822659 details
EIF3G_HUMANA4_HUMANBioGRID21832049 details
EIF3G_HUMANLMNA_HUMANBioGRID24623722 details
EIF3G_HUMANTRI14_HUMANBioGRID29053956 details
EIF3G_HUMANMTA70_HUMANBioGRID30232453 details
EIF3G_HUMANMEOX2_HUMANBioGRID32296183 details
EIF3G_HUMANOGT1_HUMANBioGRID32994395 details
EIF3G_HUMANARF6_HUMANIntAct17353931 details
EIF3G_HUMANEIF3M_HUMANBioGRID, IntAct17403899 22939629 24981860 26186194 28514442 details
EIF3G_HUMANEIF3E_HUMANBioGRID, IntAct17403899 22939629 24981860 26186194 26344197 28514442 details
EIF3G_HUMANIF5_HUMANBioGRID, HPRD26344197 9973622 details
EIF3G_HUMANP53_HUMANBioGRID29653964 details
EIF3G_HUMANSRSF3_HUMANBioGRID27381497 details
EIF3G_HUMANNREP_HUMANBioGRID25336651 details