Entity Details

Primary name TRPM2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94759
EntryNameTRPM2_HUMAN
FullNameTransient receptor potential cation channel subfamily M member 2
TaxID9606
Evidenceevidence at protein level
Length1503
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesTRPM2

GO terms

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GOName
GO:0001659 temperature homeostasis
GO:0002407 dendritic cell chemotaxis
GO:0005261 cation channel activity
GO:0005262 calcium channel activity
GO:0005272 sodium channel activity
GO:0005509 calcium ion binding
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006816 calcium ion transport
GO:0014074 response to purine-containing compound
GO:0015278 calcium-release channel activity
GO:0030659 cytoplasmic vesicle membrane
GO:0035579 specific granule membrane
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0042995 cell projection
GO:0043204 perikaryon
GO:0043312 neutrophil degranulation
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051289 protein homotetramerization
GO:0051489 regulation of filopodium assembly
GO:0070301 cellular response to hydrogen peroxide
GO:0070588 calcium ion transmembrane transport
GO:0070821 tertiary granule membrane
GO:0071277 cellular response to calcium ion
GO:0071415 cellular response to purine-containing compound
GO:0071502 cellular response to temperature stimulus
GO:0071577 zinc ion transmembrane transport
GO:0072571 mono-ADP-D-ribose binding
GO:0097028 dendritic cell differentiation
GO:0097553 calcium ion transmembrane import into cytosol
GO:0098655 cation transmembrane transport
GO:0098703 calcium ion import across plasma membrane
GO:0099604 ligand-gated calcium channel activity
GO:0101003 ficolin-1-rich granule membrane
GO:2000249 regulation of actin cytoskeleton reorganization

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasmic vesicle
Lysosome
Perikaryon

Domains

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DomainNameCategoryType
IPR000086 NUDIX hydrolase domainDomainDomain
IPR005821 Ion transport domainDomainDomain
IPR015797 NUDIX hydrolase-like domain superfamilyFamilyHomologous superfamily
IPR029594 Transient receptor potential cation channel subfamily M member 2FamilyFamily
IPR041491 TRPM, SLOG domainDomainDomain

Diseases

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Interactions

4 interactions