Entity Details

Primary name GFPT2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94808
EntryNameGFPT2_HUMAN
FullNameGlutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
TaxID9606
Evidenceevidence at protein level
Length682
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesGFPT2

GO terms

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GOName
GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0005829 cytosol
GO:0006002 fructose 6-phosphate metabolic process
GO:0006047 UDP-N-acetylglucosamine metabolic process
GO:0006048 UDP-N-acetylglucosamine biosynthetic process
GO:0006112 energy reserve metabolic process
GO:0006487 protein N-linked glycosylation
GO:0006541 glutamine metabolic process
GO:0097367 carbohydrate derivative binding
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001347 SIS domainDomainDomain
IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerisingFamilyFamily
IPR017932 Glutamine amidotransferase type 2 domainDomainDomain
IPR029055 Nucleophile aminohydrolases, N-terminalFamilyHomologous superfamily
IPR035466 GlmS/AgaS, SIS domain 1DomainDomain
IPR035490 GlmS/FrlB, SIS domain 2DomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00130 L-GlutamineDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
GFPT2_HUMANMTR1A_HUMANBioGRID, IntAct26514267 details
GFPT2_HUMANPOTE1_HUMANbhf-ucl, BioGRID21044950 details
GFPT2_HUMANUBC_HUMANBioGRID23314748 details