Entity Details

Primary name SAMP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02743
EntryNameSAMP_HUMAN
FullNameSerum amyloid P-component
TaxID9606
Evidenceevidence at protein level
Length223
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesAPCS

GO terms

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GOName
GO:0001849 complement component C1q complex binding
GO:0002674 negative regulation of acute inflammatory response
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0006457 protein folding
GO:0006953 acute-phase response
GO:0006958 complement activation, classical pathway
GO:0030169 low-density lipoprotein particle binding
GO:0030246 carbohydrate binding
GO:0042802 identical protein binding
GO:0044793 negative regulation by host of viral process
GO:0044869 negative regulation by host of viral exo-alpha-sialidase activity
GO:0044871 negative regulation by host of viral glycoprotein metabolic process
GO:0045087 innate immune response
GO:0045656 negative regulation of monocyte differentiation
GO:0046597 negative regulation of viral entry into host cell
GO:0046790 virion binding
GO:0048525 negative regulation of viral process
GO:0051082 unfolded protein binding
GO:0051131 chaperone-mediated protein complex assembly
GO:0061045 negative regulation of wound healing
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0072562 blood microparticle
GO:1903016 negative regulation of exo-alpha-sialidase activity
GO:1903019 negative regulation of glycoprotein metabolic process
GO:1990000 amyloid fibril formation

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001759 Pentraxin-relatedFamilyFamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR030476 Pentaxin, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB01651 Methyl 4,6-O-[(1R)-1-carboxyethylidene]-beta-D-galactopyranosideDrugbanksmall molecule
DB07579 Bis-1,2-{[(Z)-2-carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethaneDrugbanksmall molecule
DB07580 BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINEDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule