Entity Details

Primary name MIS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP03971
EntryNameMIS_HUMAN
FullNameMuellerian-inhibiting factor
TaxID9606
Evidenceevidence at transcript level
Length560
SequenceStatuscomplete
DateCreated1986-10-23
DateModified2021-06-02

Ontological Relatives

GenesAMH

GO terms

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GOName
GO:0001546 preantral ovarian follicle growth
GO:0001655 urogenital system development
GO:0001880 Mullerian duct regression
GO:0005102 signaling receptor binding
GO:0005160 transforming growth factor beta receptor binding
GO:0005179 hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007267 cell-cell signaling
GO:0007506 gonadal mesoderm development
GO:0007530 sex determination
GO:0007548 sex differentiation
GO:0007568 aging
GO:0008083 growth factor activity
GO:0010628 positive regulation of gene expression
GO:0014070 response to organic cyclic compound
GO:0030509 BMP signaling pathway
GO:0042493 response to drug
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:2000355 negative regulation of ovarian follicle development

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001839 Transforming growth factor-beta, C-terminalDomainDomain
IPR006799 Anti-Mullerian hormone, N-terminalDomainDomain
IPR017948 Transforming growth factor beta, conserved siteSiteConserved site
IPR021203 Muellerian-inhibiting factorFamilyFamily
IPR029034 Cystine-knot cytokineFamilyHomologous superfamily

Diseases

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