Entity Details

Primary name GDN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP07093
EntryNameGDN_HUMAN
FullNameGlia-derived nexin
TaxID9606
Evidenceevidence at protein level
Length398
SequenceStatuscomplete
DateCreated1988-04-01
DateModified2021-06-02

Ontological Relatives

GenesSERPINE2

GO terms

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GOName
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005102 signaling receptor binding
GO:0005539 glycosaminoglycan binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0007596 blood coagulation
GO:0008201 heparin binding
GO:0008285 negative regulation of cell population proliferation
GO:0010757 negative regulation of plasminogen activation
GO:0010766 negative regulation of sodium ion transport
GO:0010951 negative regulation of endopeptidase activity
GO:0010955 negative regulation of protein processing
GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling
GO:0021683 cerebellar granular layer morphogenesis
GO:0030195 negative regulation of blood coagulation
GO:0030308 negative regulation of cell growth
GO:0030334 regulation of cell migration
GO:0031091 platelet alpha granule
GO:0031232 extrinsic component of external side of plasma membrane
GO:0031594 neuromuscular junction
GO:0032940 secretion by cell
GO:0033363 secretory granule organization
GO:0042177 negative regulation of protein catabolic process
GO:0042628 mating plug formation
GO:0045861 negative regulation of proteolysis
GO:0045879 negative regulation of smoothened signaling pathway
GO:0048505 regulation of timing of cell differentiation
GO:0048711 positive regulation of astrocyte differentiation
GO:0050974 detection of mechanical stimulus involved in sensory perception
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0060291 long-term synaptic potentiation
GO:0060384 innervation
GO:0061108 seminal vesicle epithelium development
GO:0062023 collagen-containing extracellular matrix
GO:0090331 negative regulation of platelet aggregation
GO:1903561 extracellular vesicle

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000215 Serpin familyFamilyFamily
IPR023795 Serpin, conserved siteSiteConserved site
IPR023796 Serpin domainDomainDomain
IPR036186 Serpin superfamilyFamilyHomologous superfamily
IPR042178 Serpin superfamily, domain 1FamilyHomologous superfamily
IPR042185 Serpin superfamily, domain 2FamilyHomologous superfamily

Diseases

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