Entity Details

Primary name UROM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP07911
EntryNameUROM_HUMAN
FullNameUromodulin
TaxID9606
Evidenceevidence at protein level
Length640
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesUMOD

GO terms

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GOName
GO:0000255 allantoin metabolic process
GO:0000922 spindle pole
GO:0002251 organ or tissue specific immune response
GO:0003091 renal water homeostasis
GO:0003094 glomerular filtration
GO:0005201 extracellular matrix structural constituent
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005796 Golgi lumen
GO:0005929 cilium
GO:0006629 lipid metabolic process
GO:0006874 cellular calcium ion homeostasis
GO:0006883 cellular sodium ion homeostasis
GO:0006914 autophagy
GO:0006954 inflammatory response
GO:0006968 cellular defense response
GO:0007029 endoplasmic reticulum organization
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 leukocyte cell-cell adhesion
GO:0008285 negative regulation of cell population proliferation
GO:0008380 RNA splicing
GO:0009414 response to water deprivation
GO:0009986 cell surface
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0018107 peptidyl-threonine phosphorylation
GO:0019628 urate catabolic process
GO:0019864 IgG binding
GO:0019898 extrinsic component of membrane
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030643 cellular phosphate ion homeostasis
GO:0030644 cellular chloride ion homeostasis
GO:0031225 anchored component of membrane
GO:0032496 response to lipopolysaccharide
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0033555 multicellular organismal response to stress
GO:0034620 cellular response to unfolded protein
GO:0035809 regulation of urine volume
GO:0042493 response to drug
GO:0044861 protein transport into plasma membrane raft
GO:0046720 citric acid secretion
GO:0050829 defense response to Gram-negative bacterium
GO:0051223 regulation of protein transport
GO:0055075 potassium ion homeostasis
GO:0060073 micturition
GO:0060170 ciliary membrane
GO:0061077 chaperone-mediated protein folding
GO:0070062 extracellular exosome
GO:0070294 renal sodium ion absorption
GO:0072044 collecting duct development
GO:0072051 juxtaglomerular apparatus development
GO:0072218 metanephric ascending thin limb development
GO:0072221 metanephric distal convoluted tubule development
GO:0072233 metanephric thick ascending limb development
GO:0072665 protein localization to vacuole
GO:0097190 apoptotic signaling pathway
GO:0097273 creatinine homeostasis
GO:0097709 connective tissue replacement
GO:0097744 urate salt excretion
GO:1990266 neutrophil migration

Subcellular Location

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Subcellular Location
Apical cell membrane
Basolateral cell membrane
Cell projection
Secreted

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000742 EGF-like domainDomainDomain
IPR001507 Zona pellucida domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR017977 Zona pellucida domain, conserved siteSiteConserved site
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR024731 EGF domainDomainDomain

Diseases

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