Entity Details

Primary name CO7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP10643
EntryNameCO7_HUMAN
FullNameComplement component C7
TaxID9606
Evidenceevidence at protein level
Length843
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesC7

GO terms

Show/Hide Table
GOName
GO:0005576 extracellular region
GO:0005579 membrane attack complex
GO:0006883 cellular sodium ion homeostasis
GO:0006956 complement activation
GO:0006957 complement activation, alternative pathway
GO:0006958 complement activation, classical pathway
GO:0019835 cytolysis
GO:0030449 regulation of complement activation
GO:0070062 extracellular exosome

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR000436 Sushi/SCR/CCP domainDomainDomain
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR001862 Membrane attack complex component/perforin/complement C9FamilyFamily
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR003884 Factor I / membrane attack complexDomainDomain
IPR020863 Membrane attack complex component/perforin domain, conserved siteSiteConserved site
IPR020864 Membrane attack complex component/perforin (MACPF) domainDomainDomain
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved siteSiteConserved site
IPR035976 Sushi/SCR/CCP superfamilyFamilyHomologous superfamily
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR037564 Complement component C7FamilyFamily
IPR040729 Kazal-type serine protease inhibitor domainDomainDomain

Diseases

Show/Hide Table

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
CO7_HUMANCO5_HUMANBioGRID, HPRD, IntAct1387399 26841837 30552328 details
CO7_HUMANCLUS_HUMANBioGRID, HPRD8345200 details
CO7_HUMANPLMN_HUMANBioGRID, HPRD7814888 details