Entity Details

Primary name PPAP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP15309
EntryNamePPAP_HUMAN
FullNameProstatic acid phosphatase
TaxID9606
Evidenceevidence at protein level
Length386
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesACP3

GO terms

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GOName
GO:0003993 acid phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006144 purine nucleobase metabolic process
GO:0006772 thiamine metabolic process
GO:0007040 lysosome organization
GO:0008253 5'-nucleotidase activity
GO:0009117 nucleotide metabolic process
GO:0012506 vesicle membrane
GO:0016021 integral component of membrane
GO:0016311 dephosphorylation
GO:0016791 phosphatase activity
GO:0030175 filopodium
GO:0035577 azurophil granule membrane
GO:0042131 thiamine phosphate phosphatase activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043312 neutrophil degranulation
GO:0046085 adenosine metabolic process
GO:0051930 regulation of sensory perception of pain
GO:0052642 lysophosphatidic acid phosphatase activity
GO:0060168 positive regulation of adenosine receptor signaling pathway
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Lysosome membrane
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR000560 Histidine phosphatase superfamily, clade-2FamilyFamily
IPR029033 Histidine phosphatase superfamilyFamilyHomologous superfamily
IPR033379 Histidine acid phosphatase active siteSiteActive site

Diseases

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Drugs

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DrugNameSourceType
DB03390 (2R,3R)-2,3-Dihydroxy-4-oxo-4-(propylamino)butanoic acidDrugbanksmall molecule
DB03577 Alpha-Benzyl-Aminobenzyl-Phosphonic AcidDrugbanksmall molecule
DB06688 Sipuleucel-TDrugbankbiotech

Interactions

3 interactions