Entity Details

Primary name NK2R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP21452
EntryNameNK2R_HUMAN
FullNameSubstance-K receptor
TaxID9606
Evidenceevidence at protein level
Length398
SequenceStatuscomplete
DateCreated1991-05-01
DateModified2021-06-02

Ontological Relatives

GenesTACR2

GO terms

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GOName
GO:0004995 tachykinin receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006936 muscle contraction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007217 tachykinin receptor signaling pathway
GO:0007588 excretion
GO:0014057 positive regulation of acetylcholine secretion, neurotransmission
GO:0014827 intestine smooth muscle contraction
GO:0016497 substance K receptor activity
GO:0033685 negative regulation of luteinizing hormone secretion
GO:0035106 operant conditioning
GO:0036126 sperm flagellum
GO:0043117 positive regulation of vascular permeability
GO:0051602 response to electrical stimulus
GO:0061827 sperm head
GO:0070459 prolactin secretion
GO:0070474 positive regulation of uterine smooth muscle contraction
GO:0097225 sperm midpiece
GO:1902093 positive regulation of flagellated sperm motility

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000913 Neurokinin NK2 receptorFamilyFamily
IPR001681 Neurokinin receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB06660 SaredutantDrugbanksmall molecule

Interactions

4 interactions