Entity Details

Primary name LSHR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP22888
EntryNameLSHR_HUMAN
FullNameLutropin-choriogonadotropic hormone receptor
TaxID9606
Evidenceevidence at protein level
Length699
SequenceStatuscomplete
DateCreated1991-08-01
DateModified2021-04-07

Ontological Relatives

GenesLHCGR

GO terms

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GOName
GO:0001541 ovarian follicle development
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0004964 luteinizing hormone receptor activity
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0008528 G protein-coupled peptide receptor activity
GO:0008584 male gonad development
GO:0009755 hormone-mediated signaling pathway
GO:0022602 ovulation cycle process
GO:0030539 male genitalia development
GO:0032962 positive regulation of inositol trisphosphate biosynthetic process
GO:0035472 choriogonadotropin hormone receptor activity
GO:0038106 choriogonadotropin hormone binding
GO:0042700 luteinizing hormone signaling pathway
GO:0050890 cognition
GO:0071371 cellular response to gonadotropin stimulus
GO:0071373 cellular response to luteinizing hormone stimulus

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR002131 Glycoprotein hormone receptor familyFamilyFamily
IPR002273 Lutropin-choriogonadotropic hormone receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR026906 BspA type Leucine rich repeat regionRepeatRepeat
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00014 GoserelinDrugbanksmall molecule
DB00032 MenotropinsDrugbankbiotech
DB00044 Lutropin alfaDrugbankbiotech
DB00050 CetrorelixDrugbanksmall molecule
DB00097 Choriogonadotropin alfaDrugbankbiotech
DB06719 BuserelinDrugbankbiotech
DB09126 Chorionic Gonadotropin (Human)Drugbankbiotech