Entity Details

Primary name NKG2D_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP26718
EntryNameNKG2D_HUMAN
FullNameNKG2-D type II integral membrane protein
TaxID9606
Evidenceevidence at protein level
Length216
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0030101 natural killer cell activation
GO:0030154 cell differentiation
GO:0030246 carbohydrate binding
GO:0031295 T cell costimulation
GO:0034260 negative regulation of GTPase activity
GO:0038023 signaling receptor activity
GO:0042267 natural killer cell mediated cytotoxicity
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0050776 regulation of immune response
GO:2000502 negative regulation of natural killer cell chemotaxis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001304 C-type lectin-likeDomainDomain
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR033992 Natural killer cell receptor-like, C-type lectin-like domainDomainDomain
IPR042169 NKG2-D type II integral membrane proteinFamilyFamily

Diseases

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