Entity Details

Primary name CDD_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP32320
EntryNameCDD_HUMAN
FullNameCytidine deaminase
TaxID9606
Evidenceevidence at protein level
Length146
SequenceStatuscomplete
DateCreated1993-10-01
DateModified2021-06-02

Ontological Relatives

GenesCDA

GO terms

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GOName
GO:0001882 nucleoside binding
GO:0004126 cytidine deaminase activity
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0007166 cell surface receptor signaling pathway
GO:0008270 zinc ion binding
GO:0008655 pyrimidine-containing compound salvage
GO:0009972 cytidine deamination
GO:0019858 cytosine metabolic process
GO:0030308 negative regulation of cell growth
GO:0034774 secretory granule lumen
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043097 pyrimidine nucleoside salvage
GO:0043312 neutrophil degranulation
GO:0045980 negative regulation of nucleotide metabolic process
GO:0047844 deoxycytidine deaminase activity
GO:1904724 tertiary granule lumen
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Domains

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DomainNameCategoryType
IPR002125 Cytidine and deoxycytidylate deaminase domainDomainDomain
IPR006262 Cytidine deaminase, homotetramericFamilyFamily
IPR016192 APOBEC/CMP deaminase, zinc-bindingSiteBinding site
IPR016193 Cytidine deaminase-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00441 GemcitabineDrugbanksmall molecule
DB00928 AzacitidineDrugbanksmall molecule
DB00987 CytarabineDrugbanksmall molecule
DB01101 CapecitabineDrugbanksmall molecule
DB01262 DecitabineDrugbanksmall molecule
DB03185 1-Beta-Ribofuranosyl-1,3-DiazepinoneDrugbanksmall molecule
DB15694 CedazuridineDrugbanksmall molecule