Entity Details

Primary name PE2R1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP34995
EntryNamePE2R1_HUMAN
FullNameProstaglandin E2 receptor EP1 subtype
TaxID9606
Evidenceevidence at transcript level
Length402
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesPTGER1

GO terms

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GOName
GO:0004957 prostaglandin E receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006954 inflammatory response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0031748 D1 dopamine receptor binding
GO:0032496 response to lipopolysaccharide
GO:0120061 negative regulation of gastric emptying

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000708 Prostanoid EP1 receptorFamilyFamily
IPR001244 Prostaglandin DP receptorFamilyFamily
IPR008365 Prostanoid receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00297 BupivacaineDrugbanksmall molecule
DB00429 Carboprost tromethamineDrugbanksmall molecule
DB00770 AlprostadilDrugbanksmall molecule
DB00905 BimatoprostDrugbanksmall molecule
DB00917 DinoprostoneDrugbanksmall molecule
DB00929 MisoprostolDrugbanksmall molecule
DB01088 IloprostDrugbanksmall molecule
DB09211 LimaprostDrugbanksmall molecule