Entity Details

Primary name CAH8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP35219
EntryNameCAH8_HUMAN
FullNameCarbonic anhydrase-related protein
TaxID9606
Evidenceevidence at protein level
Length290
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesCA8

GO terms

Show/Hide Table
GOName
GO:0004089 carbonate dehydratase activity
GO:0005737 cytoplasm
GO:0006730 one-carbon metabolic process
GO:0008270 zinc ion binding
GO:0016836 hydro-lyase activity
GO:0048015 phosphatidylinositol-mediated signaling

Subcellular Location

Show/Hide Table

Domains

Show/Hide Table
DomainNameCategoryType
IPR001148 Alpha carbonic anhydrase domainDomainDomain
IPR018338 Carbonic anhydrase, alpha-class, conserved siteSiteConserved site
IPR023561 Carbonic anhydrase, alpha-classFamilyFamily
IPR036398 Alpha carbonic anhydrase domain superfamilyFamilyHomologous superfamily
IPR041877 Carbonic anhydrase-related protein VIIIFamilyFamily

Diseases

Show/Hide Table
Disease IDSourceNameDescription
613227 OMIMCerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3)A congenital cerebellar ataxia associated with dysarthia, quadrupedal gait and mental retardation. The disease is caused by variants affecting the gene represented in this entry.

Drugs

Show/Hide Table
DrugNameSourceType
DB00909 ZonisamideDrugbanksmall molecule