Entity Details

Primary name GRAM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51124
EntryNameGRAM_HUMAN
FullNameGranzyme M
TaxID9606
Evidenceevidence at protein level
Length257
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesGZMM

GO terms

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GOName
GO:0001913 T cell mediated cytotoxicity
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0006915 apoptotic process
GO:0008219 cell death
GO:0008236 serine-type peptidase activity
GO:0016020 membrane
GO:0019835 cytolysis
GO:0045087 innate immune response

Subcellular Location

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Subcellular Location
Cytoplasmic granule
Secreted

Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033040 Granzyme MFamilyFamily
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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