Entity Details

Primary name CATC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP53634
EntryNameCATC_HUMAN
FullNameDipeptidyl peptidase 1
TaxID9606
Evidenceevidence at protein level
Length463
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCTSC

GO terms

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GOName
GO:0001913 T cell mediated cytotoxicity
GO:0004197 cysteine-type endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005764 lysosome
GO:0005788 endoplasmic reticulum lumen
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0006508 proteolysis
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006955 immune response
GO:0007568 aging
GO:0008234 cysteine-type peptidase activity
GO:0008239 dipeptidyl-peptidase activity
GO:0010033 response to organic substance
GO:0016020 membrane
GO:0016505 peptidase activator activity involved in apoptotic process
GO:0019902 phosphatase binding
GO:0030134 COPII-coated ER to Golgi transport vesicle
GO:0031404 chloride ion binding
GO:0031642 negative regulation of myelination
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0035578 azurophil granule lumen
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0043312 neutrophil degranulation
GO:0043621 protein self-association
GO:0048208 COPII vesicle coating
GO:0051087 chaperone binding
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process
GO:1903980 positive regulation of microglial cell activation
GO:2001235 positive regulation of apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Lysosome

Domains

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DomainNameCategoryType
IPR000169 Cysteine peptidase, cysteine active siteSiteActive site
IPR000668 Peptidase C1A, papain C-terminalDomainDomain
IPR014882 Cathepsin C exclusionDomainDomain
IPR025660 Cysteine peptidase, histidine active siteSiteActive site
IPR025661 Cysteine peptidase, asparagine active siteSiteActive site
IPR036496 Cathepsin C, exclusion domain superfamilyFamilyHomologous superfamily
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily
IPR039412 Cathepsin CDomainDomain

Diseases

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