Entity Details

Primary name RAG2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55895
EntryNameRAG2_HUMAN
FullNameV(D)J recombination-activating protein 2
TaxID9606
Evidenceevidence at protein level
Length527
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesRAG2

GO terms

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GOName
GO:0002326 B cell lineage commitment
GO:0002331 pre-B cell allelic exclusion
GO:0002358 B cell homeostatic proliferation
GO:0002360 T cell lineage commitment
GO:0003682 chromatin binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005654 nucleoplasm
GO:0006325 chromatin organization
GO:0008270 zinc ion binding
GO:0030183 B cell differentiation
GO:0033077 T cell differentiation in thymus
GO:0033151 V(D)J recombination
GO:0035064 methylated histone binding
GO:0035091 phosphatidylinositol binding
GO:0042742 defense response to bacterium
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
GO:0043565 sequence-specific DNA binding
GO:0046622 positive regulation of organ growth
GO:0061630 ubiquitin protein ligase activity
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding
GO:0097519 DNA recombinase complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR004321 V-D-J recombination activating protein 2FamilyFamily
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR011043 Galactose oxidase/kelch, beta-propellerFamilyHomologous superfamily
IPR015915 Kelch-type beta propellerFamilyHomologous superfamily
IPR025162 Recombination activating protein 2, PHD domainDomainDomain

Diseases

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