Entity Details

Primary name TBA1B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP68363
EntryNameTBA1B_HUMAN
FullNameTubulin alpha-1B chain
TaxID9606
Evidenceevidence at protein level
Length451
SequenceStatuscomplete
DateCreated1987-08-13
DateModified2021-06-02

Ontological Relatives

GenesTUBA1B

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0003725 double-stranded RNA binding
GO:0003924 GTPase activity
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005881 cytoplasmic microtubule
GO:0007017 microtubule-based process
GO:0015630 microtubule cytoskeleton
GO:0030705 cytoskeleton-dependent intracellular transport
GO:0031625 ubiquitin protein ligase binding
GO:0045121 membrane raft
GO:0051301 cell division
GO:0071353 cellular response to interleukin-4

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000217 TubulinFamilyFamily
IPR002452 Alpha tubulinFamilyFamily
IPR003008 Tubulin/FtsZ, GTPase domainDomainDomain
IPR008280 Tubulin/FtsZ, C-terminalFamilyHomologous superfamily
IPR017975 Tubulin, conserved siteSiteConserved site
IPR018316 Tubulin/FtsZ, 2-layer sandwich domainDomainDomain
IPR023123 Tubulin, C-terminalFamilyHomologous superfamily
IPR036525 Tubulin/FtsZ, GTPase domain superfamilyFamilyHomologous superfamily
IPR037103 Tubulin/FtsZ-like, C-terminal domainFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01873 Epothilone DDrugbanksmall molecule
DB03010 PatupiloneDrugbanksmall molecule
DB05147 CYT997Drugbanksmall molecule
DB07574 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDEDrugbanksmall molecule

Interactions

73 interactions

InteractorPartnerSourcesPublicationsLink
TBA1B_HUMANSTA13_HUMANIntAct14697242 details
TBA1B_HUMANSMAD2_HUMANBioGRID, IntAct20195357 details
TBA1B_HUMANTM253_HUMANBioGRID, IntAct21988832 details
TBA1B_HUMANSLX1_HUMANBioGRID, IntAct21988832 details
TBA1B_HUMANTM1L1_HUMANBioGRID, MINT21900206 details
TBA1B_HUMANATRAP_HUMANBioGRID, IntAct25416956 details
TBA1B_HUMANTCPB_HUMANBioGRID, IntAct23190606 28514442 details
TBA1B_HUMANA4_HUMANIntAct, UniProt30664241 32814053 details
TBA1B_HUMANBRK1_HUMANIntAct32814053 details
TBA1B_HUMANTCPQ_HUMANIntAct32814053 details
TBA1B_HUMANSYUA_HUMANBioGRID, IntAct11698390 16216085 17893145 32814053 details
TBA1B_HUMANP85A_HUMANBioGRID, HPRD7592789 details
TBA1B_HUMANA2MG_HUMANBioGRID21163940 details
TBA1B_HUMANPSN1_HUMANBioGRID21163940 details
TBA1B_HUMANGRAM_HUMANBioGRID18523284 details
TBA1B_HUMANHDAC6_HUMANBioGRID, HPRD12606581 23703321 23798680 26382850 26643866 details
TBA1B_HUMANTERT_HUMANBioGRID23741361 details
TBA1B_HUMANTAU_HUMANBioGRID16687396 24905733 details
TBA1B_HUMANMTCL1_HUMANBioGRID23902687 details
TBA1B_HUMANSUMO2_HUMANBioGRID19394292 32786267 details
TBA1B_HUMANPTEN_HUMANBioGRID26561776 details
TBA1B_HUMANSRPK2_HUMANBioGRID26167880 details
TBA1B_HUMANCENPJ_HUMANBioGRID30530478 details
TBA1B_HUMANPTPRF_HUMANBioGRID25458010 details
TBA1B_HUMANEMAL4_HUMANBioGRID31409757 details
TBA1B_HUMANOGT1_HUMANBioGRID32994395 details
TBA1B_HUMANSIAH1_HUMANHPRD11146551 details
TBA1B_HUMANPAXI_HUMANHPRD10840040 details
TBA1B_HUMANMINK1_HUMANHPRD15032605 details
TBA1B_HUMAN1433Z_HUMANMINT15161933 details
TBA1B_HUMANTBB3_HUMANBioGRID, MINT22939629 24021646 26317901 details
TBA1B_HUMANESR1_HUMANBioGRID, HPRD, IntAct15556606 25604459 31527615 details
TBA1B_HUMANPOLH_HUMANBioGRID16824193 details
TBA1B_HUMANZMYM2_HUMANBioGRID18806873 details
TBA1B_HUMANCD3Z_HUMANBioGRID15084271 details
TBA1B_HUMANZAP70_HUMANBioGRID15084271 details
TBA1B_HUMANINO80_HUMANBioGRID20237820 details
TBA1B_HUMANRICTR_HUMANBioGRID17461779 details
TBA1B_HUMANKCND3_HUMANBioGRID17725712 details
TBA1B_HUMANSC6A3_HUMANBioGRID16216085 details
TBA1B_HUMANTBB1_HUMANBioGRID16216085 details
TBA1B_HUMANTBB5_HUMANBioGRID22939629 31409757 details
TBA1B_HUMANLEG2_HUMANBioGRID15129282 details
TBA1B_HUMANTNFB_HUMANBioGRID15129282 details
TBA1B_HUMANVDAC1_HUMANBioGRID12087096 details
TBA1B_HUMANMLP3A_HUMANBioGRID22963397 details
TBA1B_HUMANZBTB1_HUMANBioGRID24657165 details
TBA1B_HUMANAP2M1_HUMANBioGRID24189400 details
TBA1B_HUMANERRFI_HUMANBioGRID24189400 details
TBA1B_HUMANEMAL1_HUMANBioGRID24706829 details
TBA1B_HUMANGAN_HUMANBioGRID26460568 details
TBA1B_HUMANRANB9_HUMANBioGRID25659156 details
TBA1B_HUMANPIWL1_HUMANBioGRID26317901 details
TBA1B_HUMANSTMN1_HUMANBioGRID26317901 details
TBA1B_HUMANTRI18_HUMANBioGRID26748699 details
TBA1B_HUMANTRIM1_HUMANBioGRID26748699 details
TBA1B_HUMANNDUF8_HUMANBioGRID28162770 details
TBA1B_HUMANERLN2_HUMANBioGRID27462423 details
TBA1B_HUMANFLCN_HUMANBioGRID28656962 details
TBA1B_HUMANKCNH5_HUMANBioGRID18458804 details
TBA1B_HUMANPPIA_HUMANBioGRID25678563 details
TBA1B_HUMANANM8_HUMANBioGRID18320585 details
TBA1B_HUMANCENPV_HUMANBioGRID31260673 details
TBA1B_HUMANEIF3H_HUMANBioGRID32269044 details
TBA1B_HUMANMYC_HUMANHPRD7651436 details
TBA1B_HUMANTBG1_HUMANHPRD11082048 details
TBA1B_HUMANTP4A1_HUMANHPRD12235145 details
TBA1B_HUMANGRM7_HUMANHPRD11953448 details
TBA1B_HUMANPFD5_HUMANHPRD11535601 details
TBA1B_HUMANAP180_HUMANHPRD12750376 details
TBA1B_HUMANEPN2_HUMANHPRD12750376 details
TBA1B_HUMANFYN_HUMANHPRD11826099 details
TBA1B_HUMANIKBA_HUMANHPRD9372968 details