Entity Details

Primary name AT2C1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP98194
EntryNameAT2C1_HUMAN
FullNameCalcium-transporting ATPase type 2C member 1
TaxID9606
Evidenceevidence at protein level
Length919
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesATP2C1

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0005384 manganese ion transmembrane transporter activity
GO:0005388 P-type calcium transporter activity
GO:0005509 calcium ion binding
GO:0005524 ATP binding
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0006816 calcium ion transport
GO:0006828 manganese ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0008544 epidermis development
GO:0008553 P-type proton-exporting transporter activity
GO:0015410 ABC-type manganese transporter activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016887 ATP hydrolysis activity
GO:0030026 cellular manganese ion homeostasis
GO:0030145 manganese ion binding
GO:0030173 integral component of Golgi membrane
GO:0031532 actin cytoskeleton reorganization
GO:0032468 Golgi calcium ion homeostasis
GO:0032472 Golgi calcium ion transport
GO:0032580 Golgi cisterna membrane
GO:0033106 cis-Golgi network membrane
GO:0034220 ion transmembrane transport
GO:0042998 positive regulation of Golgi to plasma membrane protein transport
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046872 metal ion binding
GO:0070588 calcium ion transmembrane transport
GO:0098629 trans-Golgi network membrane organization

Subcellular Location

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Subcellular Location
Golgi apparatus

Domains

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DomainNameCategoryType
IPR001757 P-type ATPaseFamilyFamily
IPR004014 Cation-transporting P-type ATPase, N-terminalDomainDomain
IPR006068 Cation-transporting P-type ATPase, C-terminalDomainDomain
IPR006413 P-type ATPase, subfamily IIA, PMR1-typeFamilyFamily
IPR008250 P-type ATPase, A domain superfamilyFamilyHomologous superfamily
IPR018303 P-type ATPase, phosphorylation sitePTMPTM
IPR023214 HAD superfamilyFamilyHomologous superfamily
IPR023298 P-type ATPase, transmembrane domain superfamilyFamilyHomologous superfamily
IPR023299 P-type ATPase, cytoplasmic domain NFamilyHomologous superfamily
IPR030336 Calcium-transporting ATPase type 2C member 1FamilyFamily
IPR036412 HAD-like superfamilyFamilyHomologous superfamily
IPR044492 P-type ATPase, haloacid dehalogenase domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB00753 IsofluraneDrugbanksmall molecule
DB01028 MethoxyfluraneDrugbanksmall molecule
DB01189 DesfluraneDrugbanksmall molecule
DB01236 SevofluraneDrugbanksmall molecule
DB01373 CalciumDrugbanksmall molecule

Interactions

4 interactions