Entity Details

Primary name HEN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ02577
EntryNameHEN2_HUMAN
FullNameHelix-loop-helix protein 2
TaxID9606
Evidenceevidence at protein level
Length135
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesNHLH2

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006915 apoptotic process
GO:0007417 central nervous system development
GO:0007422 peripheral nervous system development
GO:0008584 male gonad development
GO:0021535 cell migration in hindbrain
GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron development
GO:0042698 ovulation cycle
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060179 male mating behavior
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR040238 Helix-loop-helix protein TAL-likeFamilyFamily

Diseases

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