Entity Details

Primary name CHIT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13231
EntryNameCHIT1_HUMAN
FullNameChitotriosidase-1
TaxID9606
Evidenceevidence at protein level
Length466
SequenceStatuscomplete
DateCreated2003-10-24
DateModified2021-06-02

Ontological Relatives

GenesCHIT1

GO terms

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GOName
GO:0000272 polysaccharide catabolic process
GO:0004568 chitinase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0006032 chitin catabolic process
GO:0006955 immune response
GO:0008061 chitin binding
GO:0008843 endochitinase activity
GO:0009617 response to bacterium
GO:0035580 specific granule lumen
GO:0043312 neutrophil degranulation
GO:0044245 polysaccharide digestion
GO:1904724 tertiary granule lumen

Subcellular Location

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Subcellular Location
Lysosome
Secreted

Domains

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DomainNameCategoryType
IPR001223 Glycoside hydrolase family 18, catalytic domainDomainDomain
IPR001579 Glycosyl hydrolases family 18 (GH18) active siteSiteActive site
IPR002557 Chitin binding domainDomainDomain
IPR011583 Chitinase IIDomainDomain
IPR017853 Glycoside hydrolase superfamilyFamilyHomologous superfamily
IPR029070 Chitinase insertion domain superfamilyFamilyHomologous superfamily
IPR036508 Chitin binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB03109 2-acetylamino-2-deoxy-b-D-allopyranoseDrugbanksmall molecule
DB03539 2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-AllopyranoseDrugbanksmall molecule
DB03632 ArgifinDrugbanksmall molecule
DB04350 ArgadinDrugbanksmall molecule
DB04404 AllosamizolineDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink