Entity Details

Primary name CYP1A2
Entity type gene
Source Source Link

Details

PrimaryID1544
RefseqGeneNG_008431
SymbolCYP1A2
Namecytochrome P450 family 1 subfamily A member 2
Chromosome15
Location15q24.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-12-20
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsCP1A2_HUMAN

GO terms

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GOName
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0005789 endoplasmic reticulum membrane
GO:0006706 steroid catabolic process
GO:0006778 porphyrin-containing compound metabolic process
GO:0006805 xenobiotic metabolic process
GO:0008203 cholesterol metabolic process
GO:0008210 estrogen metabolic process
GO:0009055 electron transfer activity
GO:0009403 toxin biosynthetic process
GO:0009791 post-embryonic development
GO:0009820 alkaloid metabolic process
GO:0010468 regulation of gene expression
GO:0016098 monoterpenoid metabolic process
GO:0016491 oxidoreductase activity
GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0017144 drug metabolic process
GO:0018894 dibenzo-p-dioxin metabolic process
GO:0019373 epoxygenase P450 pathway
GO:0019899 enzyme binding
GO:0020037 heme binding
GO:0030324 lung development
GO:0032259 methylation
GO:0032355 response to estradiol
GO:0032451 demethylase activity
GO:0032496 response to lipopolysaccharide
GO:0032787 monocarboxylic acid metabolic process
GO:0034875 caffeine oxidase activity
GO:0035902 response to immobilization stress
GO:0042572 retinol metabolic process
GO:0042737 drug catabolic process
GO:0042738 exogenous drug catabolic process
GO:0042759 long-chain fatty acid biosynthetic process
GO:0043231 intracellular membrane-bounded organelle
GO:0045333 cellular respiration
GO:0046222 aflatoxin metabolic process
GO:0046483 heterocycle metabolic process
GO:0050665 hydrogen peroxide biosynthetic process
GO:0070330 aromatase activity
GO:0070989 oxidative demethylation
GO:0071276 cellular response to cadmium ion
GO:0071280 cellular response to copper ion
GO:0097267 omega-hydroxylase P450 pathway
GO:0101020 estrogen 16-alpha-hydroxylase activity
GO:0101021 estrogen 2-hydroxylase activity
GO:0106256 hydroperoxy icosatetraenoate dehydratase activity

Diseases

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Interactions

9 interactions

InteractorPartnerSourcesPublicationsLink
CYP1A2ABHD16ABioGRID, IntAct32296183 details
CYP1A2PORBioGRID, HPRD15680923 9398194 details
CYP1A2CYB5ABioGRID15680923 details
CYP1A2CYP1A2BioGRID22738171 details
CYP1A2EPHA4BioGRID, IntAct28514442 details
CYP1A2ASAH1BioGRID, IntAct28514442 details
CYP1A2FECHBioGRID, IntAct28514442 details
CYP1A2PGRMC1BioGRID, IntAct28514442 details
CYP1A2CORO1BBioGRID, IntAct30021884 details