Entity Details

Primary name EN1
Entity type gene
Source Source Link

Details

PrimaryID2019
RefseqGeneNG_007123
SymbolEN1
Nameengrailed homeobox 1
Chromosome2
Location2q14.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-03
ModificationDate2021-06-12

Ontological Relatives

UniProt IDsHME1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001501 skeletal system development
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008344 adult locomotory behavior
GO:0009653 anatomical structure morphogenesis
GO:0009953 dorsal/ventral pattern formation
GO:0009954 proximal/distal pattern formation
GO:0016020 membrane
GO:0021549 cerebellum development
GO:0030182 neuron differentiation
GO:0030901 midbrain development
GO:0030917 midbrain-hindbrain boundary development
GO:0035115 embryonic forelimb morphogenesis
GO:0035176 social behavior
GO:0035264 multicellular organism growth
GO:0042220 response to cocaine
GO:0042756 drinking behavior
GO:0043473 pigmentation
GO:0043524 negative regulation of neuron apoptotic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048666 neuron development
GO:0061743 motor learning
GO:0071542 dopaminergic neuron differentiation
GO:1990403 embryonic brain development
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
EN1PAX6BioGRID, HPRD11069920 details
EN1TLE1BioGRID16571670 18611861 details
EN1JUNHPRD11551904 details
EN1BPTFIntAct14609955 details
EN1SMARCA1IntAct14609955 details