Entity Details

Primary name GNA13_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14344
EntryNameGNA13_HUMAN
FullNameGuanine nucleotide-binding protein subunit alpha-13
TaxID9606
Evidenceevidence at protein level
Length377
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesGNA13

GO terms

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GOName
GO:0001664 G protein-coupled receptor binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005834 heterotrimeric G-protein complex
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007266 Rho protein signal transduction
GO:0016020 membrane
GO:0030168 platelet activation
GO:0031526 brush border membrane
GO:0031584 activation of phospholipase D activity
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0031752 D5 dopamine receptor binding
GO:0042470 melanosome
GO:0043065 positive regulation of apoptotic process
GO:0046872 metal ion binding
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0070062 extracellular exosome
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation
GO:1904753 negative regulation of vascular associated smooth muscle cell migration

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Melanosome
Nucleus

Domains

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DomainNameCategoryType
IPR000469 G-protein alpha subunit, group 12/13FamilyFamily
IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunitFamilyFamily
IPR011025 G protein alpha subunit, helical insertionFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

41 interactions

InteractorPartnerSourcesPublicationsLink
GNA13_HUMANARHG1_HUMANBioGRID, HPRD, IntAct, MINT12016230 12681510 14634662 20300064 9641916 details
GNA13_HUMANAKAP3_HUMANBioGRID, HPRD11696326 details
GNA13_HUMANCADH1_HUMANBioGRID11136230 details
GNA13_HUMANCADH2_HUMANBioGRID, HPRD11136230 details
GNA13_HUMANRGS16_HUMANBioGRID, HPRD14634662 details
GNA13_HUMANPPP5_HUMANBioGRID, HPRD12176367 details
GNA13_HUMANKPCB_HUMANBioGRID, HPRD8824244 details
GNA13_HUMANKPCE_HUMANBioGRID, HPRD8824244 details
GNA13_HUMANKPCD_HUMANBioGRID, HPRD8824244 details
GNA13_HUMANRADI_HUMANBioGRID, HPRD10816569 details
GNA13_HUMANTA2R_HUMANBioGRID, HPRD10318854 10395940 10488151 12399457 15782186 8290554 details
GNA13_HUMANRIC8A_HUMANBioGRID, HPRD12509430 details
GNA13_HUMANAIP_HUMANBioGRID19390533 details
GNA13_HUMANKAPCA_HUMANBioGRID, HPRD12399457 details
GNA13_HUMANCXCR5_HUMANBioGRID, Molecular Connections23773523 details
GNA13_HUMANCXCR4_HUMANBioGRID, HPRD, Molecular Connections11994484 23773523 details
GNA13_HUMANPAR1_HUMANBioGRID, HPRD, Molecular Connections10922491 23773523 8290554 details
GNA13_HUMANPTG3L_HUMANIntAct25036637 details
GNA13_HUMANAASD1_HUMANIntAct25036637 details
GNA13_HUMANCYBP_HUMANIntAct25036637 details
GNA13_HUMANDRD5_HUMANBioGRID, HPRD12623966 details
GNA13_HUMANFAK2_HUMANBioGRID, HPRD10821841 details
GNA13_HUMANKAP2_HUMANBioGRID11696326 details
GNA13_HUMANARHGC_HUMANBioGRID, HPRD11094164 12016230 12515866 32203420 details
GNA13_HUMANMCF2_HUMANBioGRID, HPRD11062019 details
GNA13_HUMANARHGB_HUMANBioGRID, HPRD10026210 12016230 32203420 details
GNA13_HUMANM3K5_HUMANBioGRID17595347 details
GNA13_HUMANARG28_HUMANBioGRID17595347 details
GNA13_HUMANGBG2_HUMANBioGRID12399457 details
GNA13_HUMANAHR_HUMANBioGRID19390533 details
GNA13_HUMANGLI1_HUMANBioGRID26603838 details
GNA13_HUMANMTR1A_HUMANHPRD10598579 details
GNA13_HUMANS1PR3_HUMANHPRD10488065 details
GNA13_HUMANGPR17_HUMANHPRD9092554 details
GNA13_HUMANTSHR_HUMANHPRD8552586 details
GNA13_HUMANS1PR4_HUMANHPRD12767884 details
GNA13_HUMANGNA12_HUMANHPRD10026210 details
GNA13_HUMANS1PR2_HUMANHPRD10488065 details
GNA13_HUMANEDNRB_HUMANHPRD12135322 details
GNA13_HUMANCTNB1_HUMANHPRD11136230 details
GNA13_HUMANTGFR1_HUMANHPRD15761153 details