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Entity Details
Primary name
TRIPC_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q14669
EntryName
TRIPC_HUMAN
FullName
E3 ubiquitin-protein ligase TRIP12
TaxID
9606
Evidence
evidence at protein level
Length
1992
SequenceStatus
complete
DateCreated
1997-11-01
DateModified
2021-06-02
Ontological Relatives
Genes
TRIP12
GO terms
Show/Hide Table
GO
Name
GO:0000209
protein polyubiquitination
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005829
cytosol
GO:0006281
DNA repair
GO:0006511
ubiquitin-dependent protein catabolic process
GO:0006974
cellular response to DNA damage stimulus
GO:0016607
nuclear speck
GO:0045995
regulation of embryonic development
GO:0046966
thyroid hormone receptor binding
GO:0061630
ubiquitin protein ligase activity
GO:1901315
negative regulation of histone H2A K63-linked ubiquitination
GO:2000779
regulation of double-strand break repair
GO:2000780
negative regulation of double-strand break repair
Subcellular Location
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Subcellular Location
Nucleus
Domains
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Domain
Name
Category
Type
IPR000569
HECT domain
Domain
Domain
IPR004170
WWE domain
Domain
Domain
IPR011989
Armadillo-like helical
Family
Homologous superfamily
IPR016024
Armadillo-type fold
Family
Homologous superfamily
IPR035983
HECT, E3 ligase catalytic domain
Family
Homologous superfamily
IPR037197
WWE domain superfamily
Family
Homologous superfamily
Diseases
Show/Hide Table
Drugs
Show/Hide Table
Interactions
34 interactions
Interactor
Partner
Sources
Publications
Link
TRIPC_HUMAN
CSTN1_HUMAN
BioGRID, HPRD, IntAct
12421765
details
TRIPC_HUMAN
CRNS1_HUMAN
BioGRID, HPRD, IntAct
12421765
details
TRIPC_HUMAN
CELR3_HUMAN
HPRD, IntAct
12421765
unassigned5
details
TRIPC_HUMAN
MCAF1_HUMAN
HPRD, MINT
15231748
details
TRIPC_HUMAN
SMAD9_HUMAN
BioGRID, HPRD, MINT
15231748
details
TRIPC_HUMAN
MTR1A_HUMAN
BioGRID, IntAct
26514267
details
TRIPC_HUMAN
MTR1B_HUMAN
BioGRID, IntAct
26514267
details
TRIPC_HUMAN
MYC_HUMAN
BioGRID, DIP
20208519
29467282
details
TRIPC_HUMAN
ARF_HUMAN
BioGRID, DIP
20208519
22561347
23034180
24769896
27323397
details
TRIPC_HUMAN
ULA1_HUMAN
BioGRID
18627766
details
TRIPC_HUMAN
CDN2A_HUMAN
BioGRID
20208519
22561347
23034180
24769896
27323397
details
TRIPC_HUMAN
NMI_HUMAN
BioGRID
23034180
details
TRIPC_HUMAN
UB2D1_HUMAN
BioGRID
18627766
19028681
23663701
9575161
details
TRIPC_HUMAN
UB2L3_HUMAN
BioGRID
29643511
32755579
9575161
details
TRIPC_HUMAN
SOX6_HUMAN
BioGRID
23663701
details
TRIPC_HUMAN
UBC_HUMAN
BioGRID
19028681
27182664
29499138
details
TRIPC_HUMAN
UBE4B_HUMAN
BioGRID
18627766
details
TRIPC_HUMAN
PTF1A_HUMAN
BioGRID
25355311
details
TRIPC_HUMAN
SRPK2_HUMAN
BioGRID
26167880
details
TRIPC_HUMAN
ERG_HUMAN
BioGRID
27626314
details
TRIPC_HUMAN
UB2D2_HUMAN
BioGRID
29643511
details
TRIPC_HUMAN
PARP1_HUMAN
BioGRID
32755579
34079125
details
TRIPC_HUMAN
OGT1_HUMAN
BioGRID
32994395
details
TRIPC_HUMAN
THB_HUMAN
HPRD
7776974
details
TRIPC_HUMAN
UBP7_HUMAN
BioGRID, IntAct
19615732
27800609
30367141
30804394
details
TRIPC_HUMAN
PIHD1_HUMAN
IntAct
24656813
details
TRIPC_HUMAN
NPM_HUMAN
DIP
20208519
details
TRIPC_HUMAN
DISC1_HUMAN
IntAct
31413325
details
TRIPC_HUMAN
SMCE1_HUMAN
BioGRID
20829358
details
TRIPC_HUMAN
TRADD_HUMAN
BioGRID
22561347
details
TRIPC_HUMAN
GNL3_HUMAN
BioGRID
24769896
details
TRIPC_HUMAN
CPSF1_HUMAN
BioGRID
29395067
details
TRIPC_HUMAN
SHLD2_HUMAN
BioGRID
30154076
details
TRIPC_HUMAN
ECT2_HUMAN
BioGRID
32929379
details
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