Entity Details

Primary name MVP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14764
EntryNameMVP_HUMAN
FullNameMajor vault protein
TaxID9606
Evidenceevidence at protein level
Length893
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesMVP

GO terms

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GOName
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0015031 protein transport
GO:0016020 membrane
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0031953 negative regulation of protein autophosphorylation
GO:0034774 secretory granule lumen
GO:0038127 ERBB signaling pathway
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042802 identical protein binding
GO:0043312 neutrophil degranulation
GO:0048471 perinuclear region of cytoplasm
GO:0051028 mRNA transport
GO:0061099 negative regulation of protein tyrosine kinase activity
GO:0070062 extracellular exosome
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR002499 Major vault protein, N-terminalRepeatRepeat
IPR021870 Major vault protein, shoulder domainDomainDomain
IPR039059 Major vault proteinFamilyFamily
IPR040989 Major vault protein repeat domain 3DomainDomain
IPR041134 Major vault protein repeat domain 2DomainDomain
IPR041136 Major vault protein repeat domain 4DomainDomain
IPR041139 Major vault protein repeat domainDomainDomain
IPR043023 Major vault protein repeat domain superfamilyFamilyHomologous superfamily
IPR043179 Major vault protein repeat domain 2 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

76 interactions

InteractorPartnerSourcesPublicationsLink
MVP_HUMANHYES_HUMANBioGRID, IntAct21988832 details
MVP_HUMANHPT_HUMANBioGRID, IntAct21988832 details
MVP_HUMANIMA1_HUMANBioGRID, IntAct21988832 details
MVP_HUMANCYB_HUMANBioGRID, IntAct21988832 details
MVP_HUMANPLS1_HUMANBioGRID, IntAct21988832 24722188 details
MVP_HUMANGIT2_HUMANBioGRID, IntAct21988832 details
MVP_HUMANMVP_HUMANBioGRID, IntAct21988832 24722188 25416956 32296183 details
MVP_HUMANCKAP4_HUMANBioGRID, IntAct21988832 details
MVP_HUMANNNTM_HUMANBioGRID, IntAct21988832 details
MVP_HUMANPOTE1_HUMANBioGRID, IntAct21988832 details
MVP_HUMANNRF1_HUMANBioGRID, IntAct32296183 details
MVP_HUMANDTX2_HUMANBioGRID, IntAct32296183 details
MVP_HUMANUBTD2_HUMANBioGRID, IntAct32296183 details
MVP_HUMANTOLIP_HUMANBioGRID, IntAct32296183 details
MVP_HUMANNTAQ1_HUMANBioGRID, IntAct32296183 details
MVP_HUMANFND3B_HUMANBioGRID, IntAct32296183 details
MVP_HUMANPARP4_HUMANBioGRID, HPRD, IntAct10477748 11855821 28514442 details
MVP_HUMANESR1_HUMANBioGRID, HPRD9628887 details
MVP_HUMANPTEN_HUMANBioGRID, HPRD12177006 details
MVP_HUMANRIMB1_HUMANBioGRID24722188 details
MVP_HUMANDISC1_HUMANBioGRID24722188 details
MVP_HUMANDLX2_HUMANBioGRID24722188 details
MVP_HUMANATL4_HUMANBioGRID24722188 details
MVP_HUMANTLE5_HUMANBioGRID24722188 details
MVP_HUMANBANP_HUMANBioGRID24722188 details
MVP_HUMANCA094_HUMANBioGRID24722188 details
MVP_HUMANCACO2_HUMANBioGRID24722188 details
MVP_HUMANKCC2B_HUMANBioGRID24722188 details
MVP_HUMANIHO1_HUMANBioGRID24722188 details
MVP_HUMANSAXO1_HUMANBioGRID24722188 details
MVP_HUMANTET5C_HUMANBioGRID24722188 details
MVP_HUMANGOGA2_HUMANBioGRID24722188 details
MVP_HUMANKCTD9_HUMANBioGRID24722188 details
MVP_HUMANIMA4_HUMANBioGRID24722188 details
MVP_HUMANMDFI_HUMANBioGRID24722188 details
MVP_HUMANMEOX1_HUMANBioGRID24722188 details
MVP_HUMANMEOX2_HUMANBioGRID24722188 details
MVP_HUMANTRIM1_HUMANBioGRID24722188 details
MVP_HUMANMRTFA_HUMANBioGRID24722188 details
MVP_HUMANNT2NC_HUMANBioGRID24722188 details
MVP_HUMANNT2NA_HUMANBioGRID24722188 details
MVP_HUMANSTN1_HUMANBioGRID24722188 details
MVP_HUMANPIHD2_HUMANBioGRID24722188 details
MVP_HUMANPPIP1_HUMANBioGRID24722188 details
MVP_HUMANRAB3I_HUMANBioGRID24722188 details
MVP_HUMANRBPMS_HUMANBioGRID24722188 details
MVP_HUMANREL_HUMANBioGRID24722188 details
MVP_HUMANRHXF2_HUMANBioGRID24722188 details
MVP_HUMANRIM3A_HUMANBioGRID24722188 details
MVP_HUMANRN111_HUMANBioGRID24722188 details
MVP_HUMANSRTD1_HUMANBioGRID24722188 details
MVP_HUMANSKIL_HUMANBioGRID24722188 details
MVP_HUMANITF2_HUMANBioGRID24722188 details
MVP_HUMANTFCP2_HUMANBioGRID24722188 details
MVP_HUMANP53_HUMANBioGRID24722188 details
MVP_HUMANTRAF2_HUMANBioGRID24722188 details
MVP_HUMANTRI27_HUMANBioGRID24722188 details
MVP_HUMANTRI42_HUMANBioGRID24722188 details
MVP_HUMANPCH2_HUMANBioGRID24722188 details
MVP_HUMANTRIP6_HUMANBioGRID24722188 details
MVP_HUMANVAC14_HUMANBioGRID24722188 details
MVP_HUMANZBT32_HUMANBioGRID24722188 details
MVP_HUMANZMIZ2_HUMANBioGRID24722188 details
MVP_HUMANUBC_HUMANBioGRID28190767 details
MVP_HUMAN1433Z_HUMANMINT15161933 details
MVP_HUMANCOP1_HUMANBioGRID, IntAct15994960 25117710 details
MVP_HUMANFMR1_HUMANMINT21653829 details
MVP_HUMANFXR1_HUMANMINT21653829 details
MVP_HUMANFXR2_HUMANMINT21653829 details
MVP_HUMANGLUT4_HUMANBioGRID, HPRD16396496 details
MVP_HUMANTEP1_HUMANBioGRID10551828 details
MVP_HUMANU2AF2_HUMANBioGRID26641092 details
MVP_HUMANTRAF6_HUMANBioGRID30996248 details
MVP_HUMANCD276_HUMANBioGRID30082909 details
MVP_HUMANEIF3H_HUMANBioGRID32269044 details
MVP_HUMANPTN11_HUMANHPRD15133037 15588985 details