Entity Details

Primary name 2A5A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15172
EntryName2A5A_HUMAN
FullNameSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
TaxID9606
Evidenceevidence at protein level
Length486
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesPPP2R5A

GO terms

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GOName
GO:0000159 protein phosphatase type 2A complex
GO:0000775 chromosome, centromeric region
GO:0004721 phosphoprotein phosphatase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0006470 protein dephosphorylation
GO:0007165 signal transduction
GO:0016020 membrane
GO:0019888 protein phosphatase regulator activity
GO:0019900 kinase binding
GO:0030018 Z disc
GO:0031430 M band
GO:0031952 regulation of protein autophosphorylation
GO:0035307 positive regulation of protein dephosphorylation
GO:0072542 protein phosphatase activator activity
GO:0090219 negative regulation of lipid kinase activity
GO:1903077 negative regulation of protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR002554 Protein phosphatase 2A, regulatory B subunit, B56FamilyFamily
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily

Diseases

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Interactions

46 interactions

InteractorPartnerSourcesPublicationsLink
2A5A_HUMANGNL3_HUMANHPRD, IntAct16097049 details
2A5A_HUMAN2A5D_HUMANBioGRID, UniProt16541025 26344197 details
2A5A_HUMANSGO2_HUMANUniProt16541025 details
2A5A_HUMAN2AAA_HUMANBioGRID, HPRD, IntAct, MINT11856313 12370081 17245430 18782753 20220139 26344197 26496610 28330616 7592815 details
2A5A_HUMAN2AAB_HUMANBioGRID, IntAct12370081 17540176 18782753 8703017 details
2A5A_HUMANCHK2_HUMANBioGRID, HPRD, IntAct15380617 details
2A5A_HUMANAXIN1_HUMANBioGRID, MINT11297546 19131971 details
2A5A_HUMANPP2AA_HUMANBioGRID, IntAct, MINT18782753 20220139 26344197 26496610 26811472 27880917 28330616 7592815 8703017 details
2A5A_HUMANM3K3_HUMANMINT16407301 details
2A5A_HUMANDZIP1_HUMANBioGRID, IntAct, MINT21878643 32296183 details
2A5A_HUMANUSBP1_HUMANBioGRID, IntAct32296183 details
2A5A_HUMANMOS_HUMANBioGRID, IntAct26186194 28514442 32296183 details
2A5A_HUMANERIC4_HUMANBioGRID, IntAct32296183 details
2A5A_HUMANTNNT2_HUMANBioGRID, IntAct32296183 details
2A5A_HUMANSHFL_HUMANBioGRID, IntAct32296183 details
2A5A_HUMANCA021_HUMANBioGRID, IntAct32296183 details
2A5A_HUMANLIPA1_HUMANBioGRID, IntAct32296183 details
2A5A_HUMANAXIN2_HUMANBioGRID, IntAct32296183 details
2A5A_HUMANSPRE1_HUMANIntAct32814053 details
2A5A_HUMANA4_HUMANIntAct32814053 details
2A5A_HUMANAPC_HUMANBioGRID, HPRD10092233 11585828 details
2A5A_HUMANE2AK2_HUMANBioGRID, HPRD10866685 details
2A5A_HUMANCTLA4_HUMANBioGRID, HPRD11994459 details
2A5A_HUMANNEK1_HUMANBioGRID, HPRD14690447 details
2A5A_HUMANPTTG1_HUMANBioGRID24781523 details
2A5A_HUMANDAPK1_HUMANBioGRID20220139 details
2A5A_HUMANSGO1_HUMANHPRD, UniProt16541024 16541025 details
2A5A_HUMANSET_HUMANMINT17245428 details
2A5A_HUMANFMR1_HUMANIntAct31413325 details
2A5A_HUMANEPHA1_HUMANIntAct31413325 details
2A5A_HUMANBCL2_HUMANBioGRID, HPRD11929874 details
2A5A_HUMAN2A5G_HUMANBioGRID11929880 details
2A5A_HUMANESPL1_HUMANBioGRID24781523 details
2A5A_HUMAN2ABD_HUMANBioGRID20220139 details
2A5A_HUMANCDC20_HUMANBioGRID26811472 details
2A5A_HUMANCDC27_HUMANBioGRID26811472 details
2A5A_HUMANBUB1B_HUMANBioGRID26811472 details
2A5A_HUMANUBE2S_HUMANBioGRID26811472 details
2A5A_HUMANFAP20_HUMANBioGRID30789902 details
2A5A_HUMANKC1A_HUMANHPRD12062430 details
2A5A_HUMANSHC1_HUMANHPRD11884620 details
2A5A_HUMANP63_HUMANHPRD12086851 details
2A5A_HUMANJAK2_HUMANHPRD8702385 details
2A5A_HUMANBEST1_HUMANHPRD12058047 details
2A5A_HUMANTAU_HUMANHPRD12435421 details
2A5A_HUMANNOS3_HUMANHPRD11397791 12501214 details