Entity Details

Primary name MMP14
Entity type gene
Source Source Link

Details

PrimaryID4323
RefseqGeneNG_046989
SymbolMMP14
Namematrix metallopeptidase 14
Chromosome14
Location14q11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsMMP14_HUMAN

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001525 angiogenesis
GO:0001541 ovarian follicle development
GO:0001666 response to hypoxia
GO:0001935 endothelial cell proliferation
GO:0001958 endochondral ossification
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0005178 integrin binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005796 Golgi lumen
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005925 focal adhesion
GO:0006508 proteolysis
GO:0006979 response to oxidative stress
GO:0008270 zinc ion binding
GO:0008584 male gonad development
GO:0009612 response to mechanical stimulus
GO:0010831 positive regulation of myotube differentiation
GO:0010954 positive regulation of protein processing
GO:0014070 response to organic cyclic compound
GO:0016485 protein processing
GO:0022617 extracellular matrix disassembly
GO:0030198 extracellular matrix organization
GO:0030307 positive regulation of cell growth
GO:0030324 lung development
GO:0030335 positive regulation of cell migration
GO:0030574 collagen catabolic process
GO:0031012 extracellular matrix
GO:0031410 cytoplasmic vesicle
GO:0031638 zymogen activation
GO:0035987 endodermal cell differentiation
GO:0035988 chondrocyte proliferation
GO:0042470 melanosome
GO:0043615 astrocyte cell migration
GO:0043627 response to estrogen
GO:0044354 macropinosome
GO:0045111 intermediate filament cytoskeleton
GO:0045579 positive regulation of B cell differentiation
GO:0045746 negative regulation of Notch signaling pathway
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048754 branching morphogenesis of an epithelial tube
GO:0048771 tissue remodeling
GO:0048870 cell motility
GO:0051895 negative regulation of focal adhesion assembly
GO:0060322 head development
GO:0070006 metalloaminopeptidase activity
GO:0097094 craniofacial suture morphogenesis
GO:1903076 regulation of protein localization to plasma membrane
GO:1905523 positive regulation of macrophage migration
GO:1990834 response to odorant

Diseases

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Interactions

56 interactions

InteractorPartnerSourcesPublicationsLink
MMP14C1QBPBioGRID, HPRD, MINT11773076 12220632 details
MMP14ADI1HPRD, UniProt14718544 details
MMP14FURINBioGRID, IntAct, MINT20608975 21152186 8804434 details
MMP14RRADBioGRID, IntAct21988832 details
MMP14PLLPBioGRID, IntAct21988832 details
MMP14TIMP2BioGRID, HPRD, MINT24112707 8804434 9422789 9724659 details
MMP14LUMBioGRID, HPRD, MINT15466200 25304424 details
MMP14KASH5BioGRID, IntAct25416956 details
MMP14ZUP1BioGRID, IntAct32296183 details
MMP14HSD17B13BioGRID, IntAct32296183 details
MMP14STOMBioGRID, IntAct32296183 details
MMP14EBPBioGRID, IntAct32296183 details
MMP14F11RBioGRID, IntAct32296183 details
MMP14FHL3BioGRID, IntAct32296183 details
MMP14MSMO1BioGRID, IntAct32296183 details
MMP14AQP6BioGRID, IntAct32296183 details
MMP14ELOVL4BioGRID, IntAct32296183 details
MMP14TIMP1BioGRID, IntAct26264872 32814053 8804434 details
MMP14MMP3BioGRID8804434 details
MMP14TMEM31BioGRID32296183 details
MMP14TGM2BioGRID11278623 details
MMP14BCAR1BioGRID, HPRD, MINT18164686 details
MMP14ACTBMINT18164686 details
MMP14GORASP2MINT20608975 details
MMP14GOLGB1MINT20608975 details
MMP14TGOLN2MINT20608975 details
MMP14LIMK1Molecular Connections21219645 details
MMP14ENGIntAct22296769 details
MMP14FGFR2DIP20798051 details
MMP14FGFR4DIP20798051 details
MMP14LRP1BioGRID, HPRD14645246 details
MMP14SPOCK3BioGRID, HPRD11751414 details
MMP14VPS35BioGRID29891722 details
MMP14CAV1BioGRID, HPRD15466865 details
MMP14CA9BioGRID28692057 details
MMP14FBXO6BioGRID32409323 details
MMP14TIMP3HPRD8663332 details
MMP14F12HPRD10930399 details
MMP14MMP13HPRD8663255 details
MMP14KISS1HPRD12879005 details
MMP14CLDN1HPRD11382769 details
MMP14SPOCK1HPRD12810672 details
MMP14ITGAVHPRD11741954 details
MMP14TIMP4HPRD11178970 details
MMP14SDC1HPRD12464176 12904296 details
MMP14MMP2HPRD14583471 8663332 details
MMP14ACANHPRD11854269 9688535 details
MMP14CCL7HPRD10947989 12149192 details
MMP14EGFRIntAct24189400 details
MMP14CD9UniProt26686862 details
MMP14ADAM10UniProt26686862 details
MMP14TSPAN12UniProt19587294 details
MMP14SLC15A4UniProt32433612 details
MMP14MYCBioGRID29467282 details
MMP14PTPRHBioGRID28675297 details
MMP14PTPROBioGRID28675297 details