Entity Details

Primary name BAD
Entity type gene
Source Source Link

Details

PrimaryID572
RefseqGene
SymbolBAD
NameBCL2 associated agonist of cell death
Chromosome11
Location11q13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-07-30
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsBAD_HUMAN

GO terms

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GOName
GO:0001836 release of cytochrome c from mitochondria
GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:0005543 phospholipid binding
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
GO:0006007 glucose catabolic process
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007283 spermatogenesis
GO:0008289 lipid binding
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0009749 response to glucose
GO:0010508 positive regulation of autophagy
GO:0010918 positive regulation of mitochondrial membrane potential
GO:0019050 suppression by virus of host apoptotic process
GO:0019221 cytokine-mediated signaling pathway
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0021987 cerebral cortex development
GO:0030346 protein phosphatase 2B binding
GO:0032024 positive regulation of insulin secretion
GO:0032355 response to estradiol
GO:0032570 response to progesterone
GO:0033133 positive regulation of glucokinase activity
GO:0033574 response to testosterone
GO:0034201 response to oleic acid
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042493 response to drug
GO:0042542 response to hydrogen peroxide
GO:0042593 glucose homeostasis
GO:0043065 positive regulation of apoptotic process
GO:0043200 response to amino acid
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043422 protein kinase B binding
GO:0044342 type B pancreatic cell proliferation
GO:0045471 response to ethanol
GO:0045579 positive regulation of B cell differentiation
GO:0045582 positive regulation of T cell differentiation
GO:0045862 positive regulation of proteolysis
GO:0046031 ADP metabolic process
GO:0046034 ATP metabolic process
GO:0046902 regulation of mitochondrial membrane permeability
GO:0046931 pore complex assembly
GO:0050679 positive regulation of epithelial cell proliferation
GO:0051384 response to glucocorticoid
GO:0051592 response to calcium ion
GO:0060139 positive regulation of apoptotic process by virus
GO:0071247 cellular response to chromate
GO:0071260 cellular response to mechanical stimulus
GO:0071316 cellular response to nicotine
GO:0071396 cellular response to lipid
GO:0071456 cellular response to hypoxia
GO:0071889 14-3-3 protein binding
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0097191 extrinsic apoptotic signaling pathway
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097193 intrinsic apoptotic signaling pathway
GO:0097202 activation of cysteine-type endopeptidase activity
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1901216 positive regulation of neuron death
GO:1901423 response to benzene
GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
GO:1904710 positive regulation of granulosa cell apoptotic process
GO:2000078 positive regulation of type B pancreatic cell development
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Diseases

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Interactions

115 interactions

InteractorPartnerSourcesPublicationsLink
BADBCL2L1BioGRID, HPRD, I2D, IntAct, MINT10611223 10620799 11077446 11206074 11483855 11494146 11583631 12115603 12137781 15131699 15694340 15705582 15721256 16697956 18628207 19427857 19667065 20603619 20837658 21988832 25241761 25416956 26186194 26264872 26871637 27684187 28514442 29997244 31467278 31515488 31980649 32296183 32814053 7834748 9305851 9388232 9389483 9824152 details
BADBCL2BioGRID, HPRD, IntAct, MINT10611223 11483855 15694340 15849194 15990872 16697956 17446862 19168699 20603619 7834748 9305851 9388232 9463381 details
BADBCL2L2BioGRID, DIP, HPRD, IntAct10381646 11483855 12115603 15694340 16697956 20603619 22000515 32296183 details
BADSFNBioGRID, HPRD, IntAct, MINT11697890 16189514 20005908 20179209 21988832 31980649 details
BADEWSR1BioGRID, HPRD, IntAct16189514 details
BADBNIP3LIntAct9973195 details
BADPPP1CABioGRID, HPRD, IntAct10811615 17274640 details
BADGRB2IntAct17474147 details
BADYWHAHBioGRID, HPRD, IntAct11697890 17979178 21988832 28514442 31980649 9369453 details
BADYWHAZBioGRID, HPRD, IntAct, MINT11410287 11526496 11697890 17389761 19427857 19667065 20936779 21076048 21988832 23397142 25266655 25770209 28514442 31980649 details
BADYWHAEBioGRID, HPRD, IntAct11697890 17979178 20936779 21988832 31980649 9369453 details
BADYWHAGBioGRID, HPRD, IntAct10880354 20936779 28514442 31980649 details
BADCDKN1ABioGRID, IntAct21988832 details
BADKEAP1BioGRID, IntAct21988832 details
BADCREB3L3BioGRID, IntAct21988832 details
BADPRDX2BioGRID, IntAct21988832 details
BADYWHAQBioGRID, HPRD, IntAct10611223 11697890 15280438 15694340 21988832 28514442 31980649 8929531 9369453 details
BADSTEAP3BioGRID, IntAct21988832 details
BADSUMO2BioGRID, MINT21900206 details
BADYWHABBioGRID, HPRD, IntAct, MINT11697890 21900206 24255178 28514442 31980649 9369453 details
BADAKT1BioGRID, HPRD, IntAct10358075 11500364 11994280 15722337 15998799 19667065 23085457 25241761 9381178 details
BADRAF1BioGRID, HPRD, IntAct15849194 19667065 23397142 25241761 8929531 8929532 details
BADACTN2BioGRID, IntAct32296183 details
BADKRT31BioGRID, IntAct32296183 details
BADPRKACABioGRID, HPRD, IntAct10837486 10880354 10949026 11500364 12931191 19667065 31980649 details
BADCAPN1IntAct32814053 details
BADAPPIntAct32814053 details
BADBCL2A1BioGRID, HPRD10381646 11483855 15694340 details
BADMCL1BioGRID, HPRD10579309 10837489 11483855 15694340 details
BADPRKCIBioGRID15705582 details
BADPIM2BioGRID, HPRD12954615 details
BADS100A10BioGRID, HPRD9369453 details
BADRPS6KA1BioGRID, HPRD10521512 10837486 10880354 10949026 11500364 12897128 9381178 details
BADRPS6KA5BioGRID, HPRD10880354 11500364 details
BADPAK1BioGRID, HPRD10611223 15784622 15849194 16413544 19667065 details
BADBRAFBioGRID19667065 details
BADARAFBioGRID19667065 details
BADPIM1BioGRID, HPRD16403219 28620180 details
BADHRKHPRD11483855 details
BADBCL2L11MINT19427863 details
BADBAXBioGRID, MINT17274640 19427863 details
BADCISD2MINT20010695 details
BADWNK1IntAct20936779 details
BADMAPK8HPRD, IntAct14967141 23397142 details
BADCBY1BioGRID, IntAct27173435 unassigned1312 details
BADSNCABioGRID, HPRD, IntAct10407019 15978696 31980649 details
BADGIMAP5BioGRID16509771 details
BADPRKD1BioGRID20179209 details
BADPRKCEBioGRID20179209 details
BADBECN1BioGRID28518135 details
BADULK1BioGRID28518135 details
BADRPS6KA2HPRD10521512 10837486 10880354 10949026 12897128 9381178 details
BADWASF1HPRD12931191 details
BADBCL2L10HPRD11278245 9878060 details
BADPAK5HPRD10521512 10837486 10880354 12897128 9381178 details
BADPPP3CAHPRD10195903 details
BADRPS6KA3HPRD11544290 details
BADPIM3HPRD16403219 details
BADNDUFA12BioGRID, MINT24344204 details
BADLIMK1BioGRID, IntAct26496610 details
BADSYNCRIPBioGRID, IntAct26496610 details
BADSORT1BioGRID, IntAct26496610 details
BADAPTXBioGRID, IntAct28514442 details
BADKNL1BioGRID, IntAct31980649 details
BADPPP6CBioGRID, IntAct31980649 details
BADERLIN1BioGRID, IntAct31980649 details
BADIPO7BioGRID, IntAct31980649 details
BADCYC1BioGRID, IntAct31980649 details
BADHSPD1BioGRID, IntAct31980649 details
BADHSPA8BioGRID, IntAct31980649 details
BADHSPA6BioGRID, IntAct31980649 details
BADPRKACBBioGRID, IntAct31980649 details
BADCADBioGRID, IntAct31980649 details
BADABCD3BioGRID, IntAct31980649 details
BADPPP2R1ABioGRID, IntAct31980649 details
BADPPP2R1BBioGRID, IntAct31980649 details
BADEMDBioGRID, IntAct31980649 details
BADGEMIN4BioGRID, IntAct31980649 details
BADPPP2CABioGRID, IntAct31980649 details
BADPRKDCBioGRID, IntAct31980649 details
BADSLC25A3BioGRID, IntAct31980649 details
BADPRKAA1BioGRID, IntAct31980649 details
BADPPP2R5CBioGRID, IntAct31980649 details
BADKPNB1BioGRID, IntAct31980649 details
BADPPP2R5EBioGRID, IntAct31980649 details
BADSMN1BioGRID, IntAct31980649 details
BADSMN2IntAct31980649 details
BADAGKBioGRID, IntAct31980649 details
BADATAD3BBioGRID, IntAct31980649 details
BADMCUBioGRID, IntAct31980649 details
BADGLG1BioGRID, IntAct31980649 details
BADHOOK2BioGRID, IntAct31980649 details
BADIPO9BioGRID, IntAct31980649 details
BADOSBPL8BioGRID, IntAct31980649 details
BADATAD3ABioGRID, IntAct31980649 details
BADDDX20BioGRID, IntAct31980649 details
BADAKAP8LBioGRID, IntAct31980649 details
BADTIMM9BioGRID, IntAct31980649 details
BADPRKAR1ABioGRID, IntAct31980649 details
BADMTA2BioGRID, IntAct31980649 details
BADSGPL1BioGRID, IntAct31980649 details
BADHSPB1BioGRID, IntAct31980649 details
BADATP5MFBioGRID, IntAct31980649 details
BADSLC25A11BioGRID, IntAct31980649 details
BADRBBP4BioGRID, IntAct31980649 details
BADOBI1BioGRID, IntAct31980649 details
BADCAVIN1BioGRID, IntAct31980649 details
BADHDAC2BioGRID, IntAct31980649 details
BADSLC25A10BioGRID, IntAct31980649 details
BADVCPBioGRID23383273 details
BADBADBioGRID31980649 details
BADPRKCABioGRID31980649 details
BADHSPA1ABioGRID, IntAct31980649 details
BADHSPA1BIntAct31980649 details
BADHNRNPLBioGRID28611215 details