Entity Details

Primary name LARP7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ4G0J3
EntryNameLARP7_HUMAN
FullNameLa-related protein 7
TaxID9606
Evidenceevidence at protein level
Length582
SequenceStatuscomplete
DateCreated2007-03-20
DateModified2021-06-02

Ontological Relatives

GenesLARP7

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000494 box C/D RNA 3'-end processing
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006397 mRNA processing
GO:0007283 spermatogenesis
GO:0008380 RNA splicing
GO:0017070 U6 snRNA binding
GO:0030154 cell differentiation
GO:0032897 negative regulation of viral transcription
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter
GO:0048024 regulation of mRNA splicing, via spliceosome
GO:0097322 7SK snRNA binding
GO:0120259 7SK snRNP
GO:1904871 positive regulation of protein localization to Cajal body
GO:1905382 positive regulation of snRNA transcription by RNA polymerase II
GO:1990438 U6 2'-O-snRNA methylation
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR002344 Lupus La proteinFamilyFamily
IPR006630 La-type HTH domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR014886 La protein, xRRM domainDomainDomain
IPR034887 LARP7, RNA recognition motif 1DomainDomain
IPR034910 LARP7, RNA recognition motif 2DomainDomain
IPR034946 La-related protein 7, La domainDomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

21 interactions

InteractorPartnerSourcesPublicationsLink
LARP7_HUMANHEXI1_HUMANBioGRID, DIP, IntAct, MINT, UniProt18281698 18483487 24367103 25470060 26186194 26725010 28514442 29845934 details
LARP7_HUMANPR40A_HUMANBioGRID, MINT21900206 details
LARP7_HUMANMEPCE_HUMANBioGRID, UniProt17643375 18281698 18483487 24778252 26725010 29845934 details
LARP7_HUMANCSK21_HUMANBioGRID, IntAct22113938 29845934 details
LARP7_HUMANJMJD6_HUMANBioGRID, MINT23455924 details
LARP7_HUMANLRRK2_HUMANBioGRID, IntAct29513927 31046837 details
LARP7_HUMANBARD1_HUMANBioGRID22990118 32726637 details
LARP7_HUMANTIF1B_HUMANBioGRID22863883 26725010 29845934 details
LARP7_HUMANA4_HUMANBioGRID21832049 details
LARP7_HUMANBRCA1_HUMANBioGRID32726637 details
LARP7_HUMANCDK9_HUMANBioGRID, DIP, IntAct, MINT, UniProt17643375 18281698 18483487 20562857 23455922 23602568 24367103 26186194 26659056 26725010 27684187 28514442 29845934 details
LARP7_HUMANCCNT1_HUMANBioGRID, MINT, UniProt18281698 18483487 24367103 26725010 27684187 29845934 details
LARP7_HUMANDDX21_HUMANBioGRID, DIP25470060 26725010 29845934 details
LARP7_HUMANROA1_HUMANBioGRID17643375 18483487 25324306 29845934 34079125 details
LARP7_HUMANAFF1_HUMANBioGRID24367103 details
LARP7_HUMANTERF2_HUMANBioGRID20811636 details
LARP7_HUMANSIR6_HUMANBioGRID24169447 details
LARP7_HUMANTULP3_HUMANBioGRID33187986 details
LARP7_HUMANMARCS_HUMANBioGRID30942445 details
LARP7_HUMANOASL_HUMANBioGRID, IntAct30833792 details
LARP7_HUMANTERF1_HUMANBioGRID20811636 details