Entity Details

Primary name HERC2
Entity type gene
Source Source Link

Details

PrimaryID8924
RefseqGeneNG_016355
SymbolHERC2
NameHECT and RLD domain containing E3 ubiquitin protein ligase 2
Chromosome15
Location15q13.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-01-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsHERC2_HUMAN

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005814 centriole
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006302 double-strand break repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006886 intracellular protein transport
GO:0006974 cellular response to DNA damage stimulus
GO:0008270 zinc ion binding
GO:0016020 membrane
GO:0016567 protein ubiquitination
GO:0031625 ubiquitin protein ligase binding
GO:0032183 SUMO binding
GO:0061630 ubiquitin protein ligase activity

Diseases

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Interactions

398 interactions

InteractorPartnerSourcesPublicationsLink
HERC2DISC1IntAct17043677 31413325 details
HERC2USP20BioGRID, IntAct19615732 25326330 25355518 25476789 29426014 30279242 details
HERC2CDC42BioGRID, IntAct20936779 details
HERC2TP53BioGRID, MINT22653443 24722987 27259994 28977907 31665549 details
HERC2NCOA4BioGRID, IntAct25476789 26436293 28514442 29426014 30279242 details
HERC2XPABioGRID, DIP20304803 23178497 details
HERC2RNF8BioGRID, DIP20023648 22508508 22814251 25305019 26503038 details
HERC2C5AR2BioGRID, MINT28298427 details
HERC2BDKRB2BioGRID, MINT28298427 details
HERC2BRCA1BioGRID20631078 25480944 30279242 details
HERC2UBE2NBioGRID20023648 27259994 details
HERC2CALM1BioGRID15840729 details
HERC2UBCBioGRID22508508 28190767 details
HERC2HERC2BioGRID22496338 26949039 31582797 details
HERC2UBE2D3BioGRID20631078 details
HERC2STK11BioGRID27259994 details
HERC2UBE2D1BioGRID27259994 details
HERC2ERGBioGRID27626314 details
HERC2UBE2L3BioGRID29643511 details
HERC2UBE2D2BioGRID29643511 details
HERC2RNF11HPRD15231748 details
HERC2USP16BioGRID, IntAct19615732 25305019 28514442 30279242 details
HERC2KIF20ABioGRID, IntAct25476789 26496610 details
HERC2FBXL5BioGRID, IntAct24778179 28514442 30279242 details
HERC2NEURL4BioGRID, IntAct22261722 25476789 28977907 29426014 29511261 30279242 31665549 details
HERC2EME1BioGRID, IntAct25476789 29426014 details
HERC2FTH1BioGRID, IntAct25476789 29426014 details
HERC2FTLBioGRID, IntAct25476789 29426014 details
HERC2NUDCD2BioGRID, IntAct25476789 29426014 31427565 details
HERC2UBE3ABioGRID, IntAct21493713 22645313 25476789 29426014 30257870 30279242 details
HERC2PHKBBioGRID, IntAct25476789 29426014 details
HERC2EIF3MBioGRID, IntAct25476789 29426014 30279242 details
HERC2EIF3EBioGRID, IntAct25476789 29426014 30279242 details
HERC2PHKG2BioGRID, IntAct25476789 29426014 details
HERC2EIF3HBioGRID, IntAct25476789 29426014 30279242 details
HERC2PMS1BioGRID17148452 details
HERC2MDC1BioGRID20023648 details
HERC2RNF168BioGRID20023648 details
HERC2PIAS4BioGRID22508508 details
HERC2ATRIPBioGRID21775519 details
HERC2CLSPNBioGRID21775519 25326330 details
HERC2RPA3BioGRID22261722 30279242 details
HERC2RPA1BioGRID22261722 26474068 30279242 31582797 details
HERC2PSMD14BioGRID24743594 details
HERC2MUS81BioGRID25476789 details
HERC2FDFT1BioGRID25476789 details
HERC2HLA-ABioGRID25476789 details
HERC2HM13BioGRID25476789 details
HERC2BICD2BioGRID25476789 28718761 details
HERC2ZFYVE9BioGRID25476789 details
HERC2CPT1ABioGRID25476789 details
HERC2AURKBBioGRID25476789 details
HERC2DNAAF10BioGRID25476789 details
HERC2COPZ1BioGRID25476789 details
HERC2COPEBioGRID25476789 details
HERC2PRKAR2BBioGRID25476789 details
HERC2NPRL2BioGRID25480944 details
HERC2LRRK2BioGRID26355680 details
HERC2ATOH1BioGRID27542412 details
HERC2SIRT1BioGRID27259994 details
HERC2BLMBioGRID30279242 details
HERC2TOP3ABioGRID30279242 details
HERC2RMI2BioGRID30279242 details
HERC2RPA2BioGRID30279242 31582797 details
HERC2WRNBioGRID30279242 details
HERC2BARD1BioGRID30279242 details
HERC2USP33BioGRID31427565 details
HERC2MDM2BioGRID31665549 details
HERC2MPDU1BioGRID, IntAct17353931 details
HERC2DBNLBioGRID, IntAct17353931 26186194 28514442 details
HERC2SIRT3BioGRID, IntAct19343720 details
HERC2ZRANB1BioGRID, IntAct19615732 details
HERC2USP19BioGRID, IntAct19615732 details
HERC2USP42BioGRID, IntAct19615732 details
HERC2MAP1LC3BIntAct20562859 details
HERC2CDK8BioGRID, IntAct23602568 details
HERC2MAPK6BioGRID, IntAct23602568 26972000 28514442 29426014 30279242 details
HERC2MARK2BioGRID, IntAct26496610 details
HERC2KIFC3BioGRID, IntAct26496610 details
HERC2GTSE1BioGRID, IntAct26496610 details
HERC2PSMC1BioGRID, IntAct26496610 details
HERC2SMC3BioGRID, IntAct26496610 details
HERC2CHMP4BBioGRID, IntAct26496610 details
HERC2CEP290BioGRID, IntAct26638075 details
HERC2PCM1BioGRID, IntAct25476789 26638075 29426014 details
HERC2CEP162BioGRID, IntAct26638075 details
HERC2CEP104BioGRID, IntAct26638075 details
HERC2ZNRD2BioGRID, IntAct22261722 28514442 details
HERC2ARID3ABioGRID, IntAct28514442 details
HERC2CCDC136BioGRID, IntAct28514442 details
HERC2SOSTBioGRID, IntAct28514442 details
HERC2APBB1BioGRID, IntAct28514442 details
HERC2RNF166BioGRID, IntAct26186194 28514442 details
HERC2SPZ1BioGRID, IntAct26186194 28514442 details
HERC2FARP2BioGRID, IntAct28514442 details
HERC2KNOP1BioGRID, IntAct28514442 details
HERC2MAP7D2BioGRID, IntAct28514442 details
HERC2PRIMPOLBioGRID, IntAct28514442 details
HERC2ZNF286ABioGRID, IntAct28514442 details
HERC2CCDC65BioGRID, IntAct28514442 details
HERC2RNF115BioGRID, IntAct26186194 28514442 details
HERC2HOOK1BioGRID, IntAct26186194 28514442 details
HERC2BIRC6BioGRID, IntAct25476789 26186194 28514442 details
HERC2CCDC88ABioGRID, IntAct26186194 28514442 details
HERC2RABEP1BioGRID, IntAct26186194 28514442 details
HERC2LGALS3BPBioGRID, IntAct28514442 details
HERC2DNAJB5BioGRID, IntAct26186194 28514442 details
HERC2DNAJA1BioGRID, IntAct26186194 28514442 details
HERC2HSDL2BioGRID, IntAct28514442 details
HERC2FAM98ABioGRID, IntAct28514442 details
HERC2APBA2BioGRID, IntAct28514442 details
HERC2SETIntAct29426014 details
HERC2CEP170BioGRID, IntAct22261722 25476789 29426014 details
HERC2DPTIntAct29426014 details
HERC2ZBTB5BioGRID, IntAct25476789 29426014 details
HERC2CCDC180IntAct29426014 details
HERC2KRT77IntAct29426014 details
HERC2KRT17IntAct29426014 details
HERC2COPABioGRID, IntAct25476789 29426014 details
HERC2COPB2BioGRID, IntAct25476789 29426014 details
HERC2KRT6BIntAct29426014 details
HERC2GNASBioGRID, IntAct25476789 29426014 details
HERC2FLNAIntAct29426014 details
HERC2TUBB3BioGRID, IntAct25476789 29426014 details
HERC2EIF3LBioGRID, IntAct25476789 29426014 30279242 details
HERC2EIF3KBioGRID, IntAct25476789 29426014 30279242 details
HERC2MIOSBioGRID, IntAct25476789 29426014 details
HERC2CHCHD3IntAct29426014 details
HERC2EIF3CBioGRID, IntAct25476789 29426014 30279242 details
HERC2WDR24BioGRID, IntAct25476789 29426014 details
HERC2SEH1LIntAct29426014 details
HERC2GCN1IntAct29426014 details
HERC2WDR20IntAct29426014 details
HERC2WDR48IntAct29426014 details
HERC2WDR59BioGRID, IntAct25476789 29426014 details
HERC2CAMSAP1IntAct29426014 details
HERC2EIF3ABioGRID, IntAct25476789 29426014 30279242 details
HERC2EIF3IBioGRID, IntAct25476789 26186194 29426014 30279242 details
HERC2EIF4G1BioGRID, IntAct25476789 29426014 details
HERC2OCRLBioGRID, IntAct25476789 29426014 details
HERC2EIF3BBioGRID, IntAct25476789 29426014 30279242 details
HERC2KRT6CIntAct29426014 details
HERC2PHKA1BioGRID, IntAct25476789 29426014 details
HERC2PHKA2BioGRID, IntAct25476789 29426014 details
HERC2CTNNA1BioGRID, IntAct25476789 29426014 34079125 details
HERC2EIF3GBioGRID, IntAct25476789 29426014 30279242 details
HERC2EIF3DBioGRID, IntAct25476789 29426014 30279242 details
HERC2EIF3FBioGRID, IntAct29426014 30279242 details
HERC2PFDN4IntAct29426014 details
HERC2SELENOOBioGRID, IntAct25476789 29426014 details
HERC2TUBB6IntAct29426014 details
HERC2MKI67IntAct29426014 details
HERC2LRPPRCIntAct29426014 details
HERC2LMNABioGRID, IntAct25476789 29426014 details
HERC2ECI2BioGRID, IntAct22261722 29426014 details
HERC2NEK4BioGRID, MINT25798074 details
HERC2RPL13BioGRID, IntAct30021884 details
HERC2ESR1BioGRID, IntAct31527615 details
HERC2SIRT7BioGRID22586326 details
HERC2CCP110BioGRID22261722 details
HERC2SRGAP2BioGRID22261722 29511261 details
HERC2TBK1BioGRID22261722 details
HERC2TANKBioGRID22261722 details
HERC2SEC23IPBioGRID22261722 29511261 details
HERC2KTN1BioGRID22261722 details
HERC2STK33BioGRID22451720 details
HERC2CEP250BioGRID23443559 details
HERC2CCDC8BioGRID24711643 details
HERC2UCHL5BioGRID26186194 details
HERC2GET4BioGRID26186194 details
HERC2MINDY1BioGRID26186194 details
HERC2RIPK1BioGRID26186194 details
HERC2HOXD13BioGRID26186194 details
HERC2HERC3BioGRID26186194 details
HERC2FAM83HBioGRID26186194 details
HERC2RYBPBioGRID26186194 details
HERC2ODAD3BioGRID26186194 details
HERC2ETFABioGRID26344197 details
HERC2INPP4ABioGRID26344197 details
HERC2CCDC22BioGRID25476789 details
HERC2AGAP3BioGRID25476789 details
HERC2ARHGEF5BioGRID25476789 details
HERC2HERC1BioGRID25476789 details
HERC2HPS3BioGRID25476789 details
HERC2HPS5BioGRID25476789 details
HERC2TUBA1CBioGRID25476789 details
HERC2KMT2DBioGRID25476789 details
HERC2RAB34BioGRID25476789 details
HERC2ZDHHC17BioGRID25476789 details
HERC2EPHA7BioGRID25476789 details
HERC2NUP153BioGRID25476789 details
HERC2GTF3C2BioGRID25476789 details
HERC2MLF2BioGRID25476789 details
HERC2ARNTBioGRID25476789 details
HERC2RNGTTBioGRID25476789 details
HERC2CCDC186BioGRID25476789 details
HERC2TRMT2ABioGRID25476789 details
HERC2ASAH1BioGRID25476789 details
HERC2MAVSBioGRID25476789 details
HERC2CST4BioGRID25476789 details
HERC2SPTLC2BioGRID25476789 details
HERC2ZG16BBioGRID25476789 details
HERC2NCCRP1BioGRID25476789 details
HERC2VDAC2BioGRID25476789 details
HERC2KRT80BioGRID25476789 details
HERC2CSTABioGRID25476789 details
HERC2BLMHBioGRID25476789 details
HERC2PSMB4BioGRID25476789 details
HERC2PSMD1BioGRID25476789 details
HERC2PSMD11BioGRID25476789 details
HERC2PELP1BioGRID25476789 details
HERC2TEX10BioGRID25476789 29511261 details
HERC2ITPR2BioGRID25476789 details
HERC2PTPN1BioGRID25476789 details
HERC2GNA13BioGRID25476789 details
HERC2FNDC3ABioGRID25476789 details
HERC2EPCAMBioGRID25476789 details
HERC2LACTBBioGRID25476789 details
HERC2NEK11BioGRID25476789 details
HERC2HLA-EBioGRID25476789 details
HERC2LMNB2BioGRID25476789 details
HERC2MLECBioGRID25476789 details
HERC2URI1BioGRID25476789 details
HERC2PPM1BBioGRID25476789 details
HERC2OBSL1BioGRID25476789 details
HERC2COPG2BioGRID25476789 details
HERC2COPG1BioGRID25476789 details
HERC2BICD1BioGRID25476789 28718761 details
HERC2SNAPINBioGRID25476789 details
HERC2SLC30A9BioGRID25476789 details
HERC2FHOD3BioGRID25476789 details
HERC2AKAP9BioGRID25476789 details
HERC2NINBioGRID25476789 details
HERC2SLC27A4BioGRID25476789 details
HERC2ASPMBioGRID25476789 details
HERC2PEX1BioGRID25476789 details
HERC2ETAA1BioGRID25476789 details
HERC2PRR14LBioGRID25476789 details
HERC2RIC8ABioGRID25476789 details
HERC2SCO2BioGRID25476789 details
HERC2WDR62BioGRID25476789 details
HERC2ENPP1BioGRID25476789 details
HERC2MTMR3BioGRID25476789 details
HERC2CTNNB1BioGRID25476789 30279242 details
HERC2GCC2BioGRID25476789 details
HERC2LCP1BioGRID25476789 details
HERC2SPECC1LBioGRID25476789 details
HERC2SNX6BioGRID25476789 details
HERC2ARAFBioGRID25476789 details
HERC2RAF1BioGRID25476789 details
HERC2ABRBioGRID25476789 details
HERC2RER1BioGRID25476789 details
HERC2TXLNGBioGRID25476789 details
HERC2CBX2BioGRID25476789 details
HERC2SENP1BioGRID25476789 details
HERC2ATP4ABioGRID25476789 details
HERC2EXD2BioGRID25476789 details
HERC2SSX2IPBioGRID25476789 details
HERC2CDC25CBioGRID25476789 details
HERC2MYO9BBioGRID25476789 details
HERC2RADXBioGRID25476789 details
HERC2SOGA1BioGRID25476789 details
HERC2FLIIBioGRID25476789 details
HERC2FASTKD5BioGRID25476789 details
HERC2RAB5ABioGRID26355680 details
HERC2RAB5BBioGRID26355680 details
HERC2EGFRBioGRID28065597 details
HERC2DUSP26BioGRID27880917 details
HERC2RMI1BioGRID30279242 details
HERC2ESR2BioGRID29509190 details
HERC2H3-3ABioGRID29511261 details
HERC2H3-3BBioGRID29511261 details
HERC2H3-4BioGRID29511261 details
HERC2H3-5BioGRID29511261 details
HERC2CCNKBioGRID29511261 details
HERC2KIF15BioGRID29511261 details
HERC2PMELBioGRID29511261 details
HERC2EHD4BioGRID29511261 details
HERC2NOP10BioGRID29511261 details
HERC2CLK2BioGRID29511261 details
HERC2PRPF38BBioGRID29511261 details
HERC2RPS19BioGRID29511261 details
HERC2SPOUT1BioGRID29511261 details
HERC2MED19BioGRID29511261 details
HERC2TOP1BioGRID29511261 details
HERC2SLC16A1BioGRID29511261 details
HERC2POLR1FBioGRID29511261 details
HERC2BUB3BioGRID29511261 details
HERC2PLECBioGRID29511261 details
HERC2ARGLU1BioGRID29511261 details
HERC2PRPF40ABioGRID29511261 details
HERC2CLTCBioGRID29511261 details
HERC2DDX39ABioGRID29511261 details
HERC2CADBioGRID29511261 details
HERC2GAR1BioGRID29511261 details
HERC2DKC1BioGRID29511261 details
HERC2RPL35BioGRID29511261 details
HERC2SREK1BioGRID29511261 details
HERC2CLTABioGRID29511261 details
HERC2LUC7L3BioGRID29511261 details
HERC2MED4BioGRID29511261 details
HERC2HIGD1ABioGRID29511261 details
HERC2SARNPBioGRID29511261 details
HERC2PTDSS1BioGRID29511261 details
HERC2KLHDC4BioGRID29511261 details
HERC2MED30BioGRID29511261 details
HERC2ZCCHC17BioGRID29511261 details
HERC2TAF2BioGRID29511261 details
HERC2TAF1BioGRID29511261 details
HERC2TAF1LBioGRID29511261 details
HERC2MED10BioGRID29511261 details
HERC2DHX15BioGRID29511261 details
HERC2CHERPBioGRID29511261 details
HERC2ENY2BioGRID29511261 details
HERC2AQRBioGRID29511261 details
HERC2U2SURPBioGRID29511261 details
HERC2AP3S2BioGRID29511261 details
HERC2U2AF1BioGRID29511261 details
HERC2UPF1BioGRID29511261 details
HERC2LUC7L2BioGRID29511261 details
HERC2ZNF622BioGRID29511261 details
HERC2RBM25BioGRID29511261 details
HERC2PUF60BioGRID29511261 details
HERC2ERLIN2BioGRID29511261 details
HERC2MED14BioGRID29511261 details
HERC2GLYR1BioGRID29511261 details
HERC2CDK12BioGRID29511261 details
HERC2RBM39BioGRID29511261 details
HERC2U2AF2BioGRID29511261 details
HERC2MED17BioGRID29511261 details
HERC2TMEM33BioGRID29511261 details
HERC2AEBP1BioGRID29511261 details
HERC2PABPC4BioGRID29511261 details
HERC2SFSWAPBioGRID29511261 details
HERC2DDX41BioGRID29511261 details
HERC2PAXBP1BioGRID29511261 details
HERC2CCNL1BioGRID29511261 details
HERC2AP3D1BioGRID29511261 details
HERC2DDX39BBioGRID29511261 details
HERC2EIF5BBioGRID29511261 details
HERC2IPO11BioGRID29511261 details
HERC2SNRNP27BioGRID29511261 details
HERC2CFAP20BioGRID29511261 details
HERC2LMNB1BioGRID29511261 details
HERC2RPL30BioGRID29511261 details
HERC2UBR4BioGRID29511261 details
HERC2NKAPBioGRID29511261 details
HERC2TFIP11BioGRID29511261 details
HERC2SRSF11BioGRID29511261 details
HERC2AKAP17ABioGRID29511261 details
HERC2NAT10BioGRID29511261 details
HERC2SURF4BioGRID29511261 details
HERC2DDX1BioGRID29511261 details
HERC2DDX46BioGRID29511261 details
HERC2PCBP1BioGRID29511261 details
HERC2RPL22BioGRID29511261 details
HERC2PABPC1BioGRID29511261 details
HERC2DPY30BioGRID29511261 details
HERC2TAF8BioGRID29511261 details
HERC2THOC5BioGRID29511261 details
HERC2RNPS1BioGRID29511261 details
HERC2ABCF1BioGRID29511261 details
HERC2HSD17B12BioGRID29511261 details
HERC2PPIGBioGRID29511261 details
HERC2MAGOHBBioGRID29511261 details
HERC2THOC6BioGRID29511261 details
HERC2RPS9BioGRID29511261 details
HERC2LUC7LBioGRID29511261 details
HERC2XPO1BioGRID29511261 details
HERC2MED1BioGRID29511261 details
HERC2RPL35ABioGRID29511261 details
HERC2EIF4A3BioGRID29511261 details
HERC2SSBBioGRID29511261 details
HERC2TMA16BioGRID29511261 details
HERC2HNRNPH1BioGRID29511261 details
HERC2SRRM1BioGRID29511261 details
HERC2SRSF4BioGRID29511261 details
HERC2SRPK1BioGRID29511261 details
HERC2RPL7ABioGRID29511261 details
HERC2NCLBioGRID29511261 details
HERC2SNAI1BioGRID29331416 details
HERC2FBXW7BioGRID29346117 details
HERC2MYCBioGRID29467282 details
HERC2NHLRC2BioGRID31594818 details
HERC2PELI1BioGRID30987826 details
HERC2CYLDBioGRID31067453 details
HERC2PLEKHA4BioGRID31091453 details
HERC2LRRC31BioGRID33005030 details
HERC2SSBP1BioGRID32877691 details
HERC2DNAJB8BioGRID33957083 details
HERC2DNAJC28BioGRID33957083 details
HERC2DNAJC7BioGRID33957083 details
HERC2CEP135BioGRID34079125 details
HERC2LAMP2BioGRID34079125 details
HERC2NDC80BioGRID34079125 details
HERC2TRIM25BioGRID29117863 details
HERC2TNIP2BioGRID27609421 details
HERC2VIRMABioGRID29507755 details