Entity Details

Primary name UBR4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5T4S7
EntryNameUBR4_HUMAN
FullNameE3 ubiquitin-protein ligase UBR4
TaxID9606
Evidenceevidence at protein level
Length5183
SequenceStatuscomplete
DateCreated2007-05-15
DateModified2021-06-02

Ontological Relatives

GenesUBR4

GO terms

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GOName
GO:0004842 ubiquitin-protein transferase activity
GO:0005516 calmodulin binding
GO:0005654 nucleoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0008270 zinc ion binding
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016032 viral process
GO:0035579 specific granule membrane
GO:0043312 neutrophil degranulation
GO:0061630 ubiquitin protein ligase activity
GO:0070821 tertiary granule membrane
GO:0101003 ficolin-1-rich granule membrane

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR003126 Zinc finger, UBR-typeDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR025704 E3 ubiquitin ligase, UBR4FamilyFamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04959 Verpasep caltespenDrugbankbiotech
DB05483 PCL-016Drugbanksmall molecule