Entity Details

Primary name SCNBA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UI33
EntryNameSCNBA_HUMAN
FullNameSodium channel protein type 11 subunit alpha
TaxID9606
Evidenceevidence at protein level
Length1791
SequenceStatuscomplete
DateCreated2004-12-21
DateModified2021-06-02

Ontological Relatives

GenesSCN11A

GO terms

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GOName
GO:0001518 voltage-gated sodium channel complex
GO:0005244 voltage-gated ion channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0006814 sodium ion transport
GO:0019228 neuronal action potential
GO:0030424 axon
GO:0034765 regulation of ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0042493 response to drug
GO:0044299 C-fiber
GO:0051930 regulation of sensory perception of pain
GO:0070062 extracellular exosome
GO:0086010 membrane depolarization during action potential

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001696 Voltage gated sodium channel, alpha subunitFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR010526 Sodium ion transport-associatedDomainDomain
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR028821 Voltage gated sodium channel, alpha-11 subunitFamilyFamily
IPR043203 Voltage-gated cation channel calcium and sodiumFamilyFamily
IPR044564 Voltage-gated sodium channel alpha subunit, inactivation gateDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00243 RanolazineDrugbanksmall molecule
DB00273 TopiramateDrugbanksmall molecule
DB00313 Valproic acidDrugbanksmall molecule
DB00555 LamotrigineDrugbanksmall molecule
DB00564 CarbamazepineDrugbanksmall molecule
DB00776 OxcarbazepineDrugbanksmall molecule
DB00907 CocaineDrugbanksmall molecule
DB00909 ZonisamideDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB05541 BrivaracetamDrugbanksmall molecule
DB09085 TetracaineDrugbanksmall molecule
DB09088 AmylocaineDrugbanksmall molecule
DB09342 PropoxycaineDrugbanksmall molecule
DB09345 PramocaineDrugbanksmall molecule
DB11186 PentoxyverineDrugbanksmall molecule
DB13269 Dichlorobenzyl alcoholDrugbanksmall molecule
DB13746 BioallethrinDrugbanksmall molecule
DB13961 Fish oilDrugbankbiotech

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink