Entity Details

Primary name UCP3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP55916
EntryNameUCP3_HUMAN
FullNameMitochondrial uncoupling protein 3
TaxID9606
Evidenceevidence at protein level
Length312
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesUCP3

GO terms

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GOName
GO:0000303 response to superoxide
GO:0001666 response to hypoxia
GO:0005215 transporter activity
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0006629 lipid metabolic process
GO:0006631 fatty acid metabolic process
GO:0007568 aging
GO:0007584 response to nutrient
GO:0007585 respiratory gaseous exchange by respiratory system
GO:0009409 response to cold
GO:0014823 response to activity
GO:0016021 integral component of membrane
GO:0017077 oxidative phosphorylation uncoupler activity
GO:0032868 response to insulin
GO:0032870 cellular response to hormone stimulus
GO:0051384 response to glucocorticoid
GO:1902600 proton transmembrane transport
GO:1990542 mitochondrial transmembrane transport
GO:1990845 adaptive thermogenesis

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR002030 Mitochondrial carrier UCP-likeFamilyFamily
IPR018108 Mitochondrial substrate/solute carrierRepeatRepeat
IPR023395 Mitochondrial carrier domain superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
601665 OMIMObesity (OBESITY)A condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. The gene represented in this entry may be involved in disease pathogenesis.

Interactions

5 interactions