Entity Details

Primary name NPSR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6W5P4
EntryNameNPSR1_HUMAN
FullNameNeuropeptide S receptor
TaxID9606
Evidenceevidence at protein level
Length371
SequenceStatuscomplete
DateCreated2005-11-08
DateModified2021-06-02

Ontological Relatives

GenesNPSR1

GO terms

Show/Hide Table
GOName
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0005000 vasopressin receptor activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0008188 neuropeptide receptor activity
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001817 Vasopressin receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR027294 Neuropeptide S receptorFamilyFamily

Diseases

Show/Hide Table
Disease IDSourceNameDescription
608584 OMIMAsthma-related traits 2 (ASRT2)Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, dyspnea, bronchial hyperresponsiveness as assessed by methacholine challenge test, serum IgE levels, atopy and atopic dermatitis. Disease susceptibility is associated with variants affecting the gene represented in this entry.

Drugs

Show/Hide Table
DrugNameSourceType
DB01159 HalothaneDrugbanksmall molecule