Entity Details

Primary name HGD_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ93099
EntryNameHGD_HUMAN
FullNameHomogentisate 1,2-dioxygenase
TaxID9606
Evidenceevidence at protein level
Length445
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesHGD

GO terms

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GOName
GO:0004411 homogentisate 1,2-dioxygenase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006559 L-phenylalanine catabolic process
GO:0006572 tyrosine catabolic process
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0070062 extracellular exosome

Subcellular Location

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Domains

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DomainNameCategoryType
IPR005708 Homogentisate 1,2-dioxygenaseFamilyFamily
IPR011051 RmlC-like cupin domain superfamilyFamilyHomologous superfamily
IPR014710 RmlC-like jelly roll foldFamilyHomologous superfamily

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
HGD_HUMANCLD7_HUMANBioGRID, IntAct21988832 details
HGD_HUMANPCDGK_HUMANBioGRID, IntAct21988832 details
HGD_HUMANGIT2_HUMANBioGRID, IntAct21988832 details
HGD_HUMANHGD_HUMANBioGRID, HPRD, IntAct10876237 25416956 32296183 details
HGD_HUMANTERF1_HUMANbhf-ucl, BioGRID21044950 details
HGD_HUMANNTAQ1_HUMANBioGRID, IntAct32296183 details