Entity Details

Primary name GGA3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NZ52
EntryNameGGA3_HUMAN
FullNameADP-ribosylation factor-binding protein GGA3
TaxID9606
Evidenceevidence at protein level
Length723
SequenceStatuscomplete
DateCreated2001-06-20
DateModified2021-06-02

Ontological Relatives

GenesGGA3

GO terms

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GOName
GO:0005764 lysosome
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0006622 protein targeting to lysosome
GO:0006886 intracellular protein transport
GO:0010008 endosome membrane
GO:0031267 small GTPase binding
GO:0031647 regulation of protein stability
GO:0031648 protein destabilization
GO:0031901 early endosome membrane
GO:0032456 endocytic recycling
GO:0032991 protein-containing complex
GO:0034394 protein localization to cell surface
GO:0043001 Golgi to plasma membrane protein transport
GO:0043130 ubiquitin binding
GO:0044877 protein-containing complex binding
GO:0045732 positive regulation of protein catabolic process
GO:0055038 recycling endosome membrane
GO:1902430 negative regulation of amyloid-beta formation
GO:1990000 amyloid fibril formation

Subcellular Location

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Subcellular Location
Early endosome membrane
Endosome membrane
Golgi apparatus
Recycling endosome membrane

Domains

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DomainNameCategoryType
IPR002014 VHS domainDomainDomain
IPR004152 GAT domainDomainDomain
IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomainDomainDomain
IPR008153 Gamma-adaptin ear (GAE) domainDomainDomain
IPR008942 ENTH/VHSFamilyHomologous superfamily
IPR013041 Clathrin adaptor, appendage, Ig-like subdomain superfamilyFamilyHomologous superfamily
IPR027422 ADP-ribosylation factor-binding protein GGA3FamilyFamily
IPR038425 GAT domain superfamilyFamilyHomologous superfamily
IPR041198 GGA, N-GAT domainDomainDomain
IPR044111 GGA3, GAT domainDomainDomain

Diseases

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Interactions

57 interactions

InteractorPartnerSourcesPublicationsLink
GGA3_HUMANMPRI_HUMANBioGRID, HPRD, MINT11387475 11390366 11859375 12032548 12060753 14567678 16135791 16977309 details
GGA3_HUMANMPRD_HUMANBioGRID, HPRD, MINT11387475 11859375 details
GGA3_HUMANUBB_HUMANIntAct15039775 details
GGA3_HUMANTS101_HUMANBioGRID, HPRD, IntAct15039775 details
GGA3_HUMANRABE1_HUMANBioGRID, HPRD, IntAct12505986 12858162 14665628 16473621 details
GGA3_HUMANHGS_HUMANMINT15611048 details
GGA3_HUMANRNF11_HUMANBioGRID, HPRD, MINT15231748 25195858 details
GGA3_HUMANPACS1_HUMANBioGRID, HPRD, MINT16977309 details
GGA3_HUMANTRI23_HUMANBioGRID, IntAct32296183 details
GGA3_HUMANZN497_HUMANBioGRID, IntAct32296183 details
GGA3_HUMANPKHB2_HUMANBioGRID, IntAct32296183 details
GGA3_HUMANP4HA3_HUMANBioGRID, IntAct32296183 details
GGA3_HUMANDAZP2_HUMANBioGRID, IntAct32296183 details
GGA3_HUMANUPP_HUMANBioGRID, IntAct32296183 details
GGA3_HUMANTPC6A_HUMANBioGRID, IntAct32296183 details
GGA3_HUMANLITAF_HUMANBioGRID, IntAct32296183 details
GGA3_HUMANARF6_HUMANBioGRID, DIP, UniProt17804820 18199687 19327867 20848231 23143332 24056087 details
GGA3_HUMANBACE1_HUMANBioGRID, UniProt14567678 26053850 details
GGA3_HUMANGGA1_HUMANBioGRID, UniProt14638859 details
GGA3_HUMANGGA2_HUMANBioGRID, UniProt14638859 31076515 details
GGA3_HUMANGGA3_HUMANHPRD, UniProt10814529 14638859 details
GGA3_HUMANARF1_HUMANBioGRID, HPRD10747089 11301005 11950392 28100775 details
GGA3_HUMANARF3_HUMANBioGRID10749927 12221117 details
GGA3_HUMANCLH1_HUMANBioGRID, HPRD11301005 details
GGA3_HUMANVPS18_HUMANBioGRID16996030 details
GGA3_HUMANVPS11_HUMANBioGRID16996030 details
GGA3_HUMANUBC_HUMANBioGRID14660606 15494413 15701688 15966896 16135791 20484053 28190767 28581508 details
GGA3_HUMANSYNRG_HUMANBioGRID, HPRD10814529 12858162 details
GGA3_HUMANEPN4_HUMANBioGRID12858162 details
GGA3_HUMANTBC3C_HUMANBioGRID18199687 details
GGA3_HUMANTBC3A_HUMANBioGRID18199687 details
GGA3_HUMANSTAB1_HUMANBioGRID15345724 details
GGA3_HUMANCDN2A_HUMANBioGRID21517092 details
GGA3_HUMANARF_HUMANBioGRID21517092 details
GGA3_HUMANTOLIP_HUMANBioGRID15047686 details
GGA3_HUMANCYH2_HUMANBioGRID17804820 details
GGA3_HUMANADA2B_HUMANBioGRID26811329 details
GGA3_HUMANADA2A_HUMANBioGRID26811329 details
GGA3_HUMANNTRK1_HUMANBioGRID26446845 details
GGA3_HUMANLRP10_HUMANBioGRID26446845 details
GGA3_HUMANARAP3_HUMANBioGRID17314030 details
GGA3_HUMANEGFR_HUMANBioGRID29358589 details
GGA3_HUMANRN214_HUMANBioGRID32296183 details
GGA3_HUMANRS27A_HUMANHPRD15039775 details
GGA3_HUMANAFTIN_HUMANHPRD14665628 details
GGA3_HUMANTGON2_HUMANBioGRID, IntAct, MINT16977309 29568061 details
GGA3_HUMANMON2_HUMANBioGRID, MINT18418388 details
GGA3_HUMANLAPM5_HUMANBioGRID17116753 details
GGA3_HUMANNEDD4_HUMANBioGRID17116753 details
GGA3_HUMANSORT_HUMANBioGRID11390366 details
GGA3_HUMANMET_HUMANBioGRID21664574 details
GGA3_HUMANCRK_HUMANBioGRID21664574 details
GGA3_HUMANITCH_HUMANBioGRID25195858 details
GGA3_HUMANITB1_HUMANBioGRID26935970 details
GGA3_HUMANSNX17_HUMANBioGRID26935970 details
GGA3_HUMANSMAP2_HUMANBioGRID29395067 details
GGA3_HUMANAP1S2_HUMANHPRD12215646 details