Entity Details

Primary name CLC4K_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UJ71
EntryNameCLC4K_HUMAN
FullNameC-type lectin domain family 4 member K
TaxID9606
Evidenceevidence at protein level
Length328
SequenceStatuscomplete
DateCreated2006-02-21
DateModified2021-06-02

Ontological Relatives

GenesCD207

GO terms

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GOName
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005537 mannose binding
GO:0005886 plasma membrane
GO:0006898 receptor-mediated endocytosis
GO:0016021 integral component of membrane
GO:0030139 endocytic vesicle
GO:0030246 carbohydrate binding
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0031901 early endosome membrane
GO:0051607 defense response to virus

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR001304 C-type lectin-likeDomainDomain
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR018378 C-type lectin, conserved siteSiteConserved site
IPR033989 CD209-like, C-type lectin-like domainDomainDomain

Diseases

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Disease IDSourceNameDescription
613393 OMIMBirbeck granule deficiency (BIRGD)A condition characterized by the absence of Birbeck granules in epidermal Langerhans cells. Despite the lack of Birbeck granules, Langerhans cells are present in normal numbers and have normal morphologic characteristics and antigen-presenting capacity. The disease is caused by variants affecting the gene represented in this entry.

Interactions

6 interactions