Entity Details

Primary name RECQ4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94761
EntryNameRECQ4_HUMAN
FullNameATP-dependent DNA helicase Q4
TaxID9606
Evidenceevidence at protein level
Length1208
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesRECQL4

GO terms

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GOName
GO:0000405 bubble DNA binding
GO:0000723 telomere maintenance
GO:0000724 double-strand break repair via homologous recombination
GO:0000781 chromosome, telomeric region
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0006260 DNA replication
GO:0006268 DNA unwinding involved in DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0007275 multicellular organism development
GO:0009378 four-way junction helicase activity
GO:0016020 membrane
GO:0032357 oxidized purine DNA binding
GO:0032508 DNA duplex unwinding
GO:0036310 ATP-dependent DNA/DNA annealing activity
GO:0043138 3'-5' DNA helicase activity
GO:0061820 telomeric D-loop disassembly
GO:0061821 telomeric D-loop binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001650 Helicase, C-terminalDomainDomain
IPR004589 DNA helicase, ATP-dependent, RecQ typeFamilyFamily
IPR011545 DEAD/DEAH box helicase domainDomainDomain
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR021110 DNA replication/checkpoint proteinFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily

Diseases

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Interactions

35 interactions

InteractorPartnerSourcesPublicationsLink
RECQ4_HUMANPRS23_HUMANBioGRID, HPRD, IntAct16169070 details
RECQ4_HUMANPOTE1_HUMANbhf-ucl, BioGRID21044950 details
RECQ4_HUMANTERF1_HUMANbhf-ucl, BioGRID21044950 details
RECQ4_HUMANTE2IP_HUMANbhf-ucl, BioGRID21044950 29229926 details
RECQ4_HUMANACD_HUMANbhf-ucl, BioGRID21044950 details
RECQ4_HUMANEP300_HUMANBioGRID19299466 details
RECQ4_HUMANMCM10_HUMANBioGRID19696745 29229926 details
RECQ4_HUMANUBR1_HUMANBioGRID15317757 details
RECQ4_HUMANSIR1_HUMANBioGRID23382074 29229926 details
RECQ4_HUMANRAD50_HUMANBioGRID29229926 details
RECQ4_HUMANRAD51_HUMANDIP18562274 details
RECQ4_HUMANDDB1_HUMANBioGRID29229926 details
RECQ4_HUMANCUL4A_HUMANBioGRID29229926 30945288 details
RECQ4_HUMANRECQ5_HUMANBioGRID19270065 details
RECQ4_HUMANCTIP_HUMANBioGRID29229926 details
RECQ4_HUMANSLD5_HUMANBioGRID19696745 29229926 details
RECQ4_HUMANUBR2_HUMANBioGRID15317757 details
RECQ4_HUMANMRE11_HUMANBioGRID29229926 details
RECQ4_HUMANCDC45_HUMANBioGRID19696745 29229926 details
RECQ4_HUMANMCM6_HUMANBioGRID19696745 29229926 details
RECQ4_HUMANH2AX_HUMANBioGRID29229926 details
RECQ4_HUMANXRCC6_HUMANBioGRID29229926 details
RECQ4_HUMANNBN_HUMANBioGRID29229926 details
RECQ4_HUMANCDK2_HUMANBioGRID29229926 details
RECQ4_HUMANMCM2_HUMANBioGRID19696745 29229926 details
RECQ4_HUMANMCM7_HUMANBioGRID19696745 29229926 details
RECQ4_HUMANCDK1_HUMANBioGRID29229926 details
RECQ4_HUMANMCM3_HUMANBioGRID19696745 29229926 details
RECQ4_HUMANPSF2_HUMANBioGRID19696745 details
RECQ4_HUMANPSF3_HUMANBioGRID19696745 29229926 details
RECQ4_HUMANMCM4_HUMANBioGRID19696745 29229926 details
RECQ4_HUMANMCM5_HUMANBioGRID19696745 29229926 details
RECQ4_HUMANTIPIN_HUMANBioGRID19696745 29229926 details
RECQ4_HUMANPSF1_HUMANBioGRID19696745 details
RECQ4_HUMANTIM_HUMANBioGRID19696745 details