Entity Details

Primary name HEM4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP10746
EntryNameHEM4_HUMAN
FullNameUroporphyrinogen-III synthase
TaxID9606
Evidenceevidence at protein level
Length265
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesUROS

GO terms

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GOName
GO:0004852 uroporphyrinogen-III synthase activity
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006780 uroporphyrinogen III biosynthetic process
GO:0006782 protoporphyrinogen IX biosynthetic process
GO:0006783 heme biosynthetic process

Subcellular Location

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Domains

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DomainNameCategoryType
IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthaseDomainDomain
IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamilyFamilyHomologous superfamily
IPR039793 Uroporphyrinogen-III synthaseFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
HEM4_HUMANUBQL4_HUMANBioGRID, HPRD, IntAct16713569 details
HEM4_HUMANHEM4_HUMANHPRD11689424 details