Entity Details

Primary name AOFB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP27338
EntryNameAOFB_HUMAN
FullNameAmine oxidase [flavin-containing] B
TaxID9606
Evidenceevidence at protein level
Length520
SequenceStatuscomplete
DateCreated1992-08-01
DateModified2021-06-02

Ontological Relatives

GenesMAOB

GO terms

Show/Hide Table
GOName
GO:0005739 mitochondrion
GO:0005740 mitochondrial envelope
GO:0005741 mitochondrial outer membrane
GO:0006805 xenobiotic metabolic process
GO:0008131 primary amine oxidase activity
GO:0009055 electron transfer activity
GO:0009636 response to toxic substance
GO:0010044 response to aluminum ion
GO:0010269 response to selenium ion
GO:0014063 negative regulation of serotonin secretion
GO:0016021 integral component of membrane
GO:0021762 substantia nigra development
GO:0032496 response to lipopolysaccharide
GO:0042135 neurotransmitter catabolic process
GO:0042420 dopamine catabolic process
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0045471 response to ethanol
GO:0045964 positive regulation of dopamine metabolic process
GO:0050660 flavin adenine dinucleotide binding
GO:0050665 hydrogen peroxide biosynthetic process
GO:0051412 response to corticosterone
GO:0097621 monoamine oxidase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Mitochondrion outer membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR001613 Flavin amine oxidaseFamilyFamily
IPR002937 Amine oxidaseDomainDomain
IPR036188 FAD/NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00182 AmphetamineDrugbanksmall molecule
DB00184 NicotineDrugbanksmall molecule
DB00191 PhentermineDrugbanksmall molecule
DB00388 PhenylephrineDrugbanksmall molecule
DB00601 LinezolidSwissprotsmall molecule
DB00614 FurazolidoneSwissprotsmall molecule
DB00668 EpinephrineDrugbanksmall molecule
DB00721 ProcaineDrugbanksmall molecule
DB00752 TranylcypromineDrugbanksmall molecule
DB00780 PhenelzineDrugbanksmall molecule
DB00909 ZonisamideDrugbanksmall molecule
DB00915 AmantadineDrugbanksmall molecule
DB00988 DopamineDrugbanksmall molecule
DB01037 SelegilineDrugbanksmall molecule
DB01104 SertralineDrugbanksmall molecule
DB01132 PioglitazoneDrugbanksmall molecule
DB01168 ProcarbazineDrugbanksmall molecule
DB01171 MoclobemideDrugbanksmall molecule
DB01175 EscitalopramDrugbanksmall molecule
DB01247 IsocarboxazidDrugbanksmall molecule
DB01363 Ephedra sinica rootDrugbankbiotech
DB01367 RasagilineDrugbanksmall molecule
DB01442 MMDADrugbanksmall molecule
DB01472 4-MethoxyamphetamineDrugbanksmall molecule
DB01577 MetamfetamineDrugbanksmall molecule
DB01626 PargylineDrugbanksmall molecule
DB02095 IsatinDrugbanksmall molecule
DB02211 (R)-N-methyl-N-2-propynyl-1-indanamineDrugbanksmall molecule
DB02509 FarnesolDrugbanksmall molecule
DB02643 N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-PropanesulfonateDrugbanksmall molecule
DB03147 Flavin adenine dinucleotideDrugbanksmall molecule
DB03894 N-Propargyl-1(S)-AminoindanDrugbanksmall molecule
DB04147 Dodecyldimethylamine N-oxideDrugbanksmall molecule
DB04307 5-Hydroxy-N-Propargyl-1(R)-AminoindanDrugbanksmall molecule
DB04677 N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINEDrugbanksmall molecule
DB04818 IproniazidSwissprotsmall molecule
DB04820 NialamideDrugbanksmall molecule
DB04821 NomifensineDrugbanksmall molecule
DB04832 ZimelidineDrugbanksmall molecule
DB04889 BicifadineDrugbanksmall molecule
DB06654 SafinamideDrugbanksmall molecule
DB06698 BetahistineDrugbanksmall molecule
DB07512 7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDEDrugbanksmall molecule
DB07513 7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONEDrugbanksmall molecule
DB08082 N-(2-AMINOETHYL)-P-CHLOROBENZAMIDEDrugbanksmall molecule
DB08176 (1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINEDrugbanksmall molecule
DB08480 4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDANDrugbanksmall molecule
DB08516 (S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE]Drugbanksmall molecule
DB08804 Nandrolone decanoateDrugbanksmall molecule
DB09042 Tedizolid phosphateSwissprotsmall molecule
DB09130 CopperDrugbanksmall molecule
DB09363 Rauwolfia serpentina rootDrugbanksmall molecule
DB12612 OzanimodDrugbanksmall molecule
DB14569 TedizolidSwissprotsmall molecule
DB14914 Flortaucipir F-18Drugbanksmall molecule