Entity Details

Primary name CDKL1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ00532
EntryNameCDKL1_HUMAN
FullNameCyclin-dependent kinase-like 1
TaxID9606
Evidenceevidence at protein level
Length358
SequenceStatuscomplete
DateCreated1993-04-01
DateModified2021-06-02

Ontological Relatives

GenesCDKL1

GO terms

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GOName
GO:0004693 cyclin-dependent protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006468 protein phosphorylation
GO:0007507 heart development
GO:0035869 ciliary transition zone
GO:0043231 intracellular membrane-bounded organelle
GO:0070062 extracellular exosome
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1902017 regulation of cilium assembly

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule

Interactions

3 interactions