Entity Details

Primary name CO7A1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ02388
EntryNameCO7A1_HUMAN
FullNameCollagen alpha-1(VII) chain
TaxID9606
Evidenceevidence at protein level
Length2944
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesCOL7A1

GO terms

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GOName
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005590 collagen type VII trimer
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007155 cell adhesion
GO:0008544 epidermis development
GO:0030020 extracellular matrix structural constituent conferring tensile strength
GO:0030134 COPII-coated ER to Golgi transport vesicle
GO:0030198 extracellular matrix organization
GO:0030199 collagen fibril organization
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0035987 endodermal cell differentiation
GO:0048208 COPII vesicle coating
GO:0062023 collagen-containing extracellular matrix

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002035 von Willebrand factor, type ADomainDomain
IPR002223 Pancreatic trypsin inhibitor Kunitz domainDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR008160 Collagen triple helix repeatRepeatRepeat
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR020901 Proteinase inhibitor I2, Kunitz, conserved siteSiteConserved site
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily
IPR036880 Pancreatic trypsin inhibitor Kunitz domain superfamilyFamilyHomologous superfamily

Diseases

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