Entity Details

Primary name CASPC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6UXS9
EntryNameCASPC_HUMAN
FullNameInactive caspase-12
TaxID9606
Evidenceevidence at transcript level
Length341
SequenceStatuscomplete
DateCreated2008-02-05
DateModified2021-06-02

Ontological Relatives

GenesCASP12

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0042981 regulation of apoptotic process
GO:0050727 regulation of inflammatory response
GO:0072557 IPAF inflammasome complex
GO:0072559 NLRP3 inflammasome complex
GO:0097169 AIM2 inflammasome complex
GO:0097194 execution phase of apoptosis
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001309 Peptidase C14, p20 domainDomainDomain
IPR001315 CARD domainDomainDomain
IPR002138 Peptidase C14, caspase non-catalytic subunit p10DomainDomain
IPR002398 Peptidase C14 familyFamilyFamily
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR015917 Peptidase C14A, caspase catalytic domainDomainDomain
IPR029030 Caspase-like domain superfamilyFamilyHomologous superfamily
IPR033139 Peptidase family C14A, cysteine active siteSiteActive site
IPR035713 Caspase-12FamilyFamily

Diseases

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