Entity Details

Primary name PLOD2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00469
EntryNamePLOD2_HUMAN
FullNameProcollagen-lysine,2-oxoglutarate 5-dioxygenase 2
TaxID9606
Evidenceevidence at protein level
Length737
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesPLOD2

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0005506 iron ion binding
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006464 cellular protein modification process
GO:0008475 procollagen-lysine 5-dioxygenase activity
GO:0017185 peptidyl-lysine hydroxylation
GO:0030199 collagen fibril organization
GO:0030867 rough endoplasmic reticulum membrane
GO:0031418 L-ascorbic acid binding
GO:0046947 hydroxylysine biosynthetic process
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Rough endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR001006 Procollagen-lysine 5-dioxygenase, conserved siteSiteConserved site
IPR005123 Oxoglutarate/iron-dependent dioxygenaseDomainDomain
IPR006620 Prolyl 4-hydroxylase, alpha subunitDomainDomain
IPR029044 Nucleotide-diphospho-sugar transferasesFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00126 Ascorbic acidDrugbanksmall molecule