Entity Details

Primary name HMGC2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TB92
EntryNameHMGC2_HUMAN
FullName3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic
TaxID9606
Evidenceevidence at protein level
Length370
SequenceStatuscomplete
DateCreated2008-05-20
DateModified2021-06-02

Ontological Relatives

GenesHMGCLL1

GO terms

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GOName
GO:0004419 hydroxymethylglutaryl-CoA lyase activity
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006552 leucine catabolic process
GO:0006629 lipid metabolic process
GO:0016020 membrane
GO:0046872 metal ion binding
GO:0046951 ketone body biosynthetic process
GO:0048471 perinuclear region of cytoplasm

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR000891 Pyruvate carboxyltransferaseDomainDomain
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR030021 HMG-CoA lyase-like1FamilyFamily
IPR043594 HMG-CoA lyaseFamilyFamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink