Entity Details

Primary name MOT10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TF71
EntryNameMOT10_HUMAN
FullNameMonocarboxylate transporter 10
TaxID9606
Evidenceevidence at protein level
Length515
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesSLC16A10

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006590 thyroid hormone generation
GO:0006865 amino acid transport
GO:0015173 aromatic amino acid transmembrane transporter activity
GO:0015349 thyroid hormone transmembrane transporter activity
GO:0015801 aromatic amino acid transport
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0030054 cell junction
GO:0043231 intracellular membrane-bounded organelle
GO:0070327 thyroid hormone transport
GO:0070460 thyroid-stimulating hormone secretion

Subcellular Location

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Subcellular Location
Basolateral cell membrane
Cell membrane

Domains

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DomainNameCategoryType
IPR011701 Major facilitator superfamilyFamilyFamily
IPR020846 Major facilitator superfamily domainDomainDomain
IPR030762 Monocarboxylate transporter 10FamilyFamily
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00117 HistidineDrugbanksmall molecule
DB00119 Pyruvic acidDrugbanksmall molecule
DB00120 PhenylalanineDrugbanksmall molecule
DB00123 L-LysineDrugbanksmall molecule
DB00125 ArginineDrugbanksmall molecule
DB00128 Aspartic acidDrugbanksmall molecule
DB00130 L-GlutamineDrugbanksmall molecule
DB00133 SerineDrugbanksmall molecule
DB00134 MethionineDrugbanksmall molecule
DB00135 TyrosineDrugbanksmall molecule
DB00138 CystineDrugbanksmall molecule
DB00142 Glutamic acidDrugbanksmall molecule
DB00145 GlycineDrugbanksmall molecule
DB00149 LeucineDrugbanksmall molecule
DB00150 TryptophanDrugbanksmall molecule
DB00151 CysteineDrugbanksmall molecule
DB00156 ThreonineDrugbanksmall molecule
DB00160 AlanineDrugbanksmall molecule
DB00161 ValineDrugbanksmall molecule
DB00167 IsoleucineDrugbanksmall molecule
DB00172 ProlineDrugbanksmall molecule
DB00174 AsparagineDrugbanksmall molecule
DB00279 LiothyronineDrugbanksmall molecule
DB01235 LevodopaDrugbanksmall molecule
DB01583 LiotrixDrugbanksmall molecule
DB01746 D-LeucineSwissprotsmall molecule
DB01786 D-AlanineDrugbanksmall molecule
DB02556 D-PhenylalanineDrugbanksmall molecule
DB02952 2-aminoisobutyric acidDrugbanksmall molecule
DB03107 beta-AlanineDrugbanksmall molecule
DB03225 D-TryptophanDrugbanksmall molecule
DB03839 D-TyrosineSwissprotsmall molecule
DB03929 D-SerineDrugbanksmall molecule
DB04398 Lactic acidDrugbanksmall molecule
DB06262 DroxidopaDrugbanksmall molecule

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
MOT10_HUMANTM14B_HUMANBioGRID, IntAct32296183 details
MOT10_HUMANINSI2_HUMANBioGRID, IntAct32296183 details
MOT10_HUMANFUND2_HUMANBioGRID, IntAct32296183 details
MOT10_HUMANRGAP1_HUMANHPRD11278976 details